OBSERVATION ON THE EFFECT OF QINGHAOSU IN TREATING CHLOROQUINE RESISTANT MALARIA:REPORT OF 65 CASES

Anti-Malaria Coordinating Group for Clinical Research on Qinghao; Hainan; Guangdong

doi:10.13288/j.11-2166/r.1979.01.019

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OBSERVATION ON THE EFFECT OF QINGHAOSU IN TREATING CHLOROQUINE RESISTANT MALARIA:REPORT OF 65 CASES

更新时间：2021-11-20

- OBSERVATION ON THE EFFECT OF QINGHAOSU IN TREATING CHLOROQUINE RESISTANT MALARIA:REPORT OF 65 CASES
- Journal of Traditional Chinese Medicine Issue 1, Pages: 12-16(1979)
- 作者机构：
  
  广东海南青蒿抗疟临床研究协作组
- 作者简介：
- 基金信息：
- DOI：10.13288/j.11-2166/r.1979.01.019
  CLC：
- Published：1979
- 稿件说明：
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[1].青蒿素治疗抗氯喹疟疾65例的效果观察[J].新医药学杂志,1979(01):12-16.

Anti-Malaria Coordinating Group for Clinical Research on Qinghao, Hainan, Guangdong. OBSERVATION ON THE EFFECT OF QINGHAOSU IN TREATING CHLOROQUINE RESISTANT MALARIA:REPORT OF 65 CASES[J]. Journal of Traditional Chinese Medicine1979, (1): 12-16.
[1].青蒿素治疗抗氯喹疟疾65例的效果观察[J].新医药学杂志,1979(01):12-16. DOI： 10.13288/j.11-2166/r.1979.01.019.

Anti-Malaria Coordinating Group for Clinical Research on Qinghao, Hainan, Guangdong. OBSERVATION ON THE EFFECT OF QINGHAOSU IN TREATING CHLOROQUINE RESISTANT MALARIA:REPORT OF 65 CASES[J]. Journal of Traditional Chinese Medicine1979, (1): 12-16. DOI： 10.13288/j.11-2166/r.1979.01.019.

摘要

在海南岛的抗性疟区

采用口服青蒿素5.4克或肌注青蒿素0.8～1.0克的3天疗程的方案

对65例当地儿童和外来成人的抗氯喹疟疾病例进行治疗观察

结果比同期使用磷酸咯茶啶等抗疟药疗效更为显著。认为这是目前治疗抗氯喹疟疾效果较好而又安全的方案。文内对青蒿素的抗疟作用、治疗后的复燃问题和影响疗效的有关因素进行了分析讨论

认为青蒿素属于杀血裂殖体剂抗疟药

在治疗过程中必须伍用伯喹

才能有效清除恶性疟配子体和防止间日疟复发。

Abstract

In the Hainan drug-resistant malaria area

a project of 3-day’s course treatment（Qing- haosu 5.4 g orally or 0.8-1.0 g intramuscularly）was administered to 65 chloroquine- resistant malarial cases

including local children and outside adults.It is more effective as compared with those treated by Pyronaridine phosphate at the sameperiod.The authors hold that this is a better and safer project.The anti-malarial effect of Qinghaosu

the recrudescence after treatment and the factors affecting its effect are analyzed and discussed. It is suggested that Qinghaosu is a schizonticide.It must be used in combination with primaquinine in order to eradicate gametocyte of malignant malaria and prevent the recurrence of tertian malaria.

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