In responding to febrile syndrome of Qi - deficiency and exuberant poisoning due to exogenous causes. Li Dongyuan of the Jin Dynasty proposed the method of antipyretic method with drugs of sweet and Warm nature

embodying the treating principle of supporting body resistance and anti - poisoning. Thus

he established the principles of invigorating the interior

ascending the Yang - principle and reducing fire by formulating a series of celebrated recipes including Decoction of Invigorating Qi and Nourishing Interior. Decoction of Bloodtonic with Radix Angelica Sinensis. demonstrating the treating principle varied on the concrete condition of body - pathogen conflict

warning the use of attacking methods in febrile disease regardless of whatever the conditions.