Experimental Study on the Protective Action of Weitongling on Gastric Mucosa.

doi:10.13288/j.11-2166/r.1995.01.026

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Experimental Study on the Protective Action of Weitongling on Gastric Mucosa.

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- Experimental Study on the Protective Action of Weitongling on Gastric Mucosa.
- Journal of Traditional Chinese Medicine Issue 1, Pages: 44-46(1995)
- 作者机构：
  
  1. 安徽中医学院
  2. 安徽医科大学
  3. 安徽医科大学安徽合肥市梅山路,230038
- 作者简介：
- 基金信息：
- DOI：10.13288/j.11-2166/r.1995.01.026
  CLC： R285.5
- Published：1995
- 稿件说明：
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[1]鄢顺琴,凤良元,苏英豪,陈向涛,许家林.胃痛灵对胃粘膜保护作用的实验研究[J].中医杂志,1995(01):44-46+4.

Experimental Study on the Protective Action of Weitongling on Gastric Mucosa.[J]. Journal of Traditional Chinese Medicine1995, (1): 44-46.
[1]鄢顺琴,凤良元,苏英豪,陈向涛,许家林.胃痛灵对胃粘膜保护作用的实验研究[J].中医杂志,1995(01):44-46+4. DOI： 10.13288/j.11-2166/r.1995.01.026.

Experimental Study on the Protective Action of Weitongling on Gastric Mucosa.[J]. Journal of Traditional Chinese Medicine1995, (1): 44-46. DOI： 10.13288/j.11-2166/r.1995.01.026.

摘要

采用氨水诱发大鼠萎缩性胃炎和醋酸引发溃疡模型

观察胃痛灵对胃粘膜的保护作用。用粘液组化染色、AgNOR染色、免疫组化染色及鸟居明法对冰醋酸涂抹造模的大鼠愈合性胃溃疡再生粘膜进行了定量观察

并对胃痛灵治疗后和自然愈合的溃疡再生粘膜进行比较;对大鼠萎缩性胃炎进行急慢性炎细胞密度计数和胃体腺长度及胃体粘膜PAS（+）层厚度的观测。结果显示胃痛灵对胃粘膜有良好的保护作用。

Abstract

Atrophic gastritis and gastric ulcer in rat models were induced with liquid ammonium and acetic acid respec- tively. Observation was made on the protective action of Weitongling on gastric mucosa. Quantitative observation was made on the regenerated mucosa of healing gastric ulcer by mucous histochemical staining

Ag-NoR staining

immuno - histo - chemical staining

and Forii Akira method in models induced by rubbing of glacial acetic acid. Comparison was also made between the above models after treated with Weitongling and that of natural healing mucosa. Further observations were made by density counting of acute and chronic inflammatory cells in atrophic gastrilis in rats

length of glands in the fundus

as well as thickness of PAS （ + ） layer in mucosa of gastric fundus. Results showed that Weitongling yields satisfactory results of protecting the gastric mucosa.

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