Influence of Moxibustion in Different Qualities and Quantities on Metabolism of Central and Peripheral 5-HT in Rat of Experimental Yang-Deficiency

doi:10.13288/j.11-2166/r.1996.02.029

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Influence of Moxibustion in Different Qualities and Quantities on Metabolism of Central and Peripheral 5-HT in Rat of Experimental Yang-Deficiency

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- Influence of Moxibustion in Different Qualities and Quantities on Metabolism of Central and Peripheral 5-HT in Rat of Experimental Yang-Deficiency
- Journal of Traditional Chinese Medicine Issue 2, Pages: 111-112(1996)
- 作者机构：
  
  1. 南京中医学院针灸系
  2. 南京中医学院针灸系南京市汉中路,210029
- 作者简介：
- 基金信息：
- DOI：10.13288/j.11-2166/r.1996.02.029
  CLC： R245.8
- Published：1996
- 稿件说明：
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[1]张京英,刘农虞,张蕊,卞慧敏.不同灸质、灸量对实验性阳虚大鼠中枢及外周5—HT代谢的影响[J].中医杂志,1996(02):111-112+68.

Influence of Moxibustion in Different Qualities and Quantities on Metabolism of Central and Peripheral 5-HT in Rat of Experimental Yang-Deficiency[J]. Journal of Traditional Chinese Medicine1996, (2): 111-112.
[1]张京英,刘农虞,张蕊,卞慧敏.不同灸质、灸量对实验性阳虚大鼠中枢及外周5—HT代谢的影响[J].中医杂志,1996(02):111-112+68. DOI： 10.13288/j.11-2166/r.1996.02.029.

Influence of Moxibustion in Different Qualities and Quantities on Metabolism of Central and Peripheral 5-HT in Rat of Experimental Yang-Deficiency[J]. Journal of Traditional Chinese Medicine1996, (2): 111-112. DOI： 10.13288/j.11-2166/r.1996.02.029.

摘要

本文采用荧光检测方法观察了不同灸质、灸量对利血平化脾阳虚大鼠外周和中枢5-羟色胺（5-HT）神经递质及其代谢产物含量的影响。实验结果显示

实验性脾阳虚大鼠外周及中枢5—HT含量均显著下降（P<0.05）

艾灸“足三里”穴可使其含量升高。其中强刺激可明显升高中枢大脑皮层5—HT含量（P<0.05）

弱刺激能使外用血中5—HT含量明显提高（P<0.05）。烟条强弱刺激对实验性脾阳虚大鼠外周和中枢5—HT含量均无调整作用。提示艾灸的作用明显优于烟灸

其作用产生和强弱与艾灸的药、热等多重刺激及刺激量的强、弱有关。

Abstract

By adopting fluorescence testing method

we observed the contents of central and peripheral 5 - HT

nerve transmitter and its metabolites in reserpinized hypos-plenic function rats by different qualities and quantities of moxibustion. Results showed that in experimental hyposplenic function rats

there was a marked lowering of contents of central .and peripheral 5 -HT （P< 0. 05）. Moxibustion on Zusanli point greatly increased its contents. When strong stimulus was administered

5-HT contents in cerebral contex markedly increased （P<0. 05）

while weak stimulus markedly increased that in peripheral blood （P<0. 05）. Stimulation with cigarette didn"t yield such results

suggesting the superior action of moxibustion to cigarette. The strength of action was related to the amount and intensity of stimulation.

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