Three kinds of TCM therapy

i.e. blood- activating stasis femoving （leech. Rhizoma Ligustici chuanx-iong. 1st group）

spleen- strenthening and phleg-mdissipating （Rhizoma pinellia. Poria tangerine peel. Radix Glycyrrhiza. and fluid of bamboo sap 2nd group） and simultaneous therapy on phlegm and stasis （3rd group）

were applied morphologically in animal model to observe their influence on the lipid level and lipid plaque formation in the aortic intima of experimental hyper lipidemic rabbit. Results revealed that all 3 methods markedly lowered the serum TC

TG. LDL-C and LPO contents and inhibited the formation of aorticintimal lipid plaque. Its action in the 1st group and that in the atromid - s group were similar. However

the lowering of serum TC. LDL- C and ami-formation of lipid plaque in the phlegm dissipating group was better in the 2nd or blood-activating stasis removing group. In all the 3 groups

the 3rd group revealed the best results. When compared with the 1st group and atromid - S group

the difference was very significant in lowering of serum TC. LDL - C and anti -formation of lipid plaque

and was also a bit better than the 2nd group

morphological and biochemical studies revealed that it changed identically with the changes in serum LDL - C and LPO. or. in other words

the higher the contents of blood TC. LDL -C. the higher the concentration of LPO. and the higher the percentage of plaque formation. The degree of plaque formation under the microscope revealed the same correlative changes

suggesting that the accumulation of LPO as a result of lipid metabolic disturbance

increase of blood TC. TG. LDL - C contents were the major causes of injury of arterial intima and lipid plaque formation.