Determination of Platelet-Granular Membranous Protein and Endothelin in Blood Stasis Patient

doi:10.13288/j.11-2166/r.1996.04.030

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Determination of Platelet-Granular Membranous Protein and Endothelin in Blood Stasis Patient

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- Determination of Platelet-Granular Membranous Protein and Endothelin in Blood Stasis Patient
- Journal of Traditional Chinese Medicine Issue 4, Pages: 239-240(1996)
- 作者机构：
  
  1. 上海医科大学附属华山医院中医科
  2. 上海医科大学附属华山医院化验室上海乌鲁木齐路12号,200040
- 作者简介：
- 基金信息：
- DOI：10.13288/j.11-2166/r.1996.04.030
  CLC： R255.7
- Published：1996
- 稿件说明：
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[1]石志芸,施赛珠,陈剑秋,李晓明,许小凤.血瘀证患者血小板α—颗粒膜蛋白、内皮素测定[J].中医杂志,1996(04):239-240+196.

Determination of Platelet-Granular Membranous Protein and Endothelin in Blood Stasis Patient[J]. Journal of Traditional Chinese Medicine1996, (4): 239-240.
[1]石志芸,施赛珠,陈剑秋,李晓明,许小凤.血瘀证患者血小板α—颗粒膜蛋白、内皮素测定[J].中医杂志,1996(04):239-240+196. DOI： 10.13288/j.11-2166/r.1996.04.030.

Determination of Platelet-Granular Membranous Protein and Endothelin in Blood Stasis Patient[J]. Journal of Traditional Chinese Medicine1996, (4): 239-240. DOI： 10.13288/j.11-2166/r.1996.04.030.

摘要

本文以血小板α-颗粒膜蛋白（GMP—140）及内皮素（ET）为血小板活化、内皮细胞功能受损的指标。观察病种为心血管疾病、肾脏病及Ⅱ型糖尿病。结果显示:3种疾病组的血浆GMP—140、ET皆明显高于正常对照组（P<0.01及<0.001）。证实上述3种疾病组中存在着血小板活化及血管内皮细胞受损现象

并发现3种疾病中的血瘀证患者其GMP—140、ET值升高尤为明显

其值均显著高于无血瘀证患者。

Abstract

Platelet a - GMP - 140

ET were used as indices of activation of platelet

functional injury to endothelial cells. Cardiovascular diseases

nephropathy and II type diabetes were selected forobservation. Results showed that the plasmal GMP-140 and ET were all markedly higher than that of the controlled group （P <0. 01 and <0. 001）

demonstrating that there are injuries to the activation of platelet and vascular endothelial cells. It was also found that inpatients with blood - stasis syndrome in the above 3 kinds of diseases

the increase of GMP-140

ET values were even more conspicuous

with markedly increased values as compared with that of patients without blood stasis.

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