Study on Rheumatoid Arthritis of Wind-cold-dampnes Type and Wind-heat-dampness Type Bi-Syndrome

doi:10.13288/j.11-2166/r.1996.06.028

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Study on Rheumatoid Arthritis of Wind-cold-dampnes Type and Wind-heat-dampness Type Bi-Syndrome

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- Study on Rheumatoid Arthritis of Wind-cold-dampnes Type and Wind-heat-dampness Type Bi-Syndrome
- Journal of Traditional Chinese Medicine Issue 6, Pages: 361-365(1996)
- 作者机构：
  
  1. 第一军医大学中医系内科
  2. 第一军医大学实验动物中心
  3. 第一军医大学珠江医院
  4. 第一军医大学南方医院同位素科广州市工业大道,510282
  5. 第一军医大学中医系内科第一军医大学实验动物中心第一军医大学珠江医院第一军医大学南方医院同位素科广州市工业大道,510282
- 作者简介：
- 基金信息：
- DOI：10.13288/j.11-2166/r.1996.06.028
  CLC： R-332
- Published：1996
- 稿件说明：
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[1]肖长虹,顾为望,李留洋,郭琳琅,谢卫兵,袁进,郑普德.类风湿性关节炎风寒湿痹与风湿热痹动物模型研究[J].中医杂志,1996(06):361-365+324.

Study on Rheumatoid Arthritis of Wind-cold-dampnes Type and Wind-heat-dampness Type Bi-Syndrome[J]. Journal of Traditional Chinese Medicine1996, (6): 361-365.
[1]肖长虹,顾为望,李留洋,郭琳琅,谢卫兵,袁进,郑普德.类风湿性关节炎风寒湿痹与风湿热痹动物模型研究[J].中医杂志,1996(06):361-365+324. DOI： 10.13288/j.11-2166/r.1996.06.028.

Study on Rheumatoid Arthritis of Wind-cold-dampnes Type and Wind-heat-dampness Type Bi-Syndrome[J]. Journal of Traditional Chinese Medicine1996, (6): 361-365. DOI： 10.13288/j.11-2166/r.1996.06.028.

摘要

本研究在大鼠胶原诱导性关节炎（CIA）的基础上给予风寒湿、风湿热刺激及葡萄球菌肠毒素B（SEB）外涂。结果显示

单纯风寒湿、风湿热不增加CIA的发病率及炎症积分

也不改变炎症关节的表面温度

但风湿热能显著提高雌性鼠炎症关节的

99m

Tc含量。在葡萄球菌肠毒素（SEB）外涂时

风寒湿能显著增加雄性鼠的炎症积分（与单纯SEB比较）

且显著提高雄性鼠的DTH反应能力（与风湿热比较）;风湿热则能显著增加雌性鼠炎症关节的

99m

Tc含量（与风寒湿比较）。在SEB外涂时

风湿热能显著增加雌性鼠的炎症关节表面温度

但风湿热与风寒湿均显著降低雄性鼠的炎症关节表面温度。

Abstract

The experiment was conducted in rats with CIA on which wind - cold - dampness

wind - heat -dampness stimulation and topical rubbing of SEB were given. Results showed that

wind - cold- dampness or wind - heat - dampness alone didn’t increase the incidence of CIA and integration of inflammation

norchange the surface temperature of the affected joint. However

wind -heat -dampness markedly increased the content of 99mTc of affected joint in female rats. When SEC was rubbed on the surface

wind -cold -dampness markedly increases the integration of inflammation in male rats （as compared with pure SEB）. and markedly increased the DTH reaction of male rats （as compared with wind -heat- dampness） . Whereas wind - heat dampness markedly increased the content of 99mTc of affected joints in female rats （ as compared with wind - cold - dampness） when topically applied SEB. wind - heat - dampness markedly increased the surface temperature of affected joint in female rats

while wind- heat - dampness and wind - cold - dampness markedly lowered that in the male rats.

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