Clinical and Experimental Studies on Influence of Zhuyu Huatan Decoction on Intracranial Pressure in Acute Cases of Cerebral Hemorrhage[J]. Journal of Traditional Chinese Medicine1997, (11): 662-665.
Clinical and Experimental Studies on Influence of Zhuyu Huatan Decoction on Intracranial Pressure in Acute Cases of Cerebral Hemorrhage[J]. Journal of Traditional Chinese Medicine1997, (11): 662-665.DOI: 10.13288/j.11-2166/r.1997.11.016.
Clinical and Experimental Studies on Influence of Zhuyu Huatan Decoction on Intracranial Pressure in Acute Cases of Cerebral Hemorrhage
The effect of the Zhuyu Huatan Decoction (ZHD) plus general therapy was observed in 44 cases with western drug as control. Continuous monitoving on the lowering intracranial pressure effect of ZHD and mannitol was made on 20 cases of acute cerebral hemorrhage at the basilar gonglion region by intraventricular pressure monitoring method. The effect of both remedies for lowering intracranial pressure was observed on experimental cerebral edema in rabbit by injecting olive oil through common carotid artery. Results: ZHD plus general therapy group yielded better action on improving consciousness than that of the western drug group. Clinically
the amplitude of decrease of intracranial pressure was 40. 44%. The action is mild and protracted than that in the mannitol group
with mild rising and no " rebound"
the amplitude of decreased pressure is smaller than that of the mannitol group. Animal experiments yielded the similar results as that of clinical therapy. yet the amplitude of lowering pressure was greater in the ZHD group than the mannitol group
the result was just the reverse as compared with that clinically. This deserve further study.