Effects of Du Su Qing on Humoral Immunity and Subgroups of T-Lymphocytes in the Patient of Senile Bacterial Pneumonia

doi:10.13288/j.11-2166/r.2001.07.020

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Effects of Du Su Qing on Humoral Immunity and Subgroups of T-Lymphocytes in the Patient of Senile Bacterial Pneumonia

更新时间：2021-11-20

- Effects of Du Su Qing on Humoral Immunity and Subgroups of T-Lymphocytes in the Patient of Senile Bacterial Pneumonia
- Journal of Traditional Chinese Medicine Issue 7, Pages: 411-414(2001)
- 作者机构：
  
  1. 河南中医学院老年医学研究室
  2. 河南省人民医院老年医学研究所
  3. 河南省人民医院老年医学研究所郑州市金水区东明路1号,450008
- 作者简介：
- 基金信息：
- DOI：10.13288/j.11-2166/r.2001.07.020
  CLC： R259.6
- Published：2001
- 稿件说明：
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[1]李建生,程龙,李素云,马利军,王凯,陈现亮,吴记珍.毒素清对老年细菌性肺炎患者体液免疫和T细胞亚群的影响[J].中医杂志,2001(07):411-414+8.

Effects of Du Su Qing on Humoral Immunity and Subgroups of T-Lymphocytes in the Patient of Senile Bacterial Pneumonia[J]. Journal of Traditional Chinese Medicine2001, (7): 411-414.
[1]李建生,程龙,李素云,马利军,王凯,陈现亮,吴记珍.毒素清对老年细菌性肺炎患者体液免疫和T细胞亚群的影响[J].中医杂志,2001(07):411-414+8. DOI： 10.13288/j.11-2166/r.2001.07.020.

Effects of Du Su Qing on Humoral Immunity and Subgroups of T-Lymphocytes in the Patient of Senile Bacterial Pneumonia[J]. Journal of Traditional Chinese Medicine2001, (7): 411-414. DOI： 10.13288/j.11-2166/r.2001.07.020.

摘要

为了评价毒素清治疗老年细菌性肺炎（痰热壅肺或气阴两虚证或痰热壅肺兼气阴两虚证）的临床疗效

观察其体液和细胞免疫功能的变化及中药毒素清对其影响。以老年人肺炎患者为研究对象

按照随机对照原则

在西医常规治疗基础上

将其分为治疗组（毒素清口服液治疗）和对照组（西医常规治疗）

以量化评分标准为手段

并选择健康老年人为对照

观察治疗前后外周血中IgA、IgG、IgM

（补体3）、C

（补体4）、T细胞亚群CD

和CD

、CD

及其比值的变化。结果:治疗组33例中

痊愈10例（30.30％）、显效16例（48.48％）、好转5例（15.15％）

有效率（93.93％）;对照组31例中分别为5例（16.13％）、6例（19.35％）、15例（48.39％）

有效率（83.87％）。两组疗效有显著性差异。老年人肺炎患者IgA、IgG、IgM及C

、CD

水平显著高于健康老年组;治疗后

治疗组较治疗前除C

外均有明显改善

接近健康老年组水平

并较对照组为优。表明毒素清配合西医常规治疗老年细菌性肺炎（痰热壅肺、气阴两虚证）具有明显疗效

其作用机理可能与以下方面有关:（1）降低患者体内显著升高的IgA、IgG、IgM与C

水平。（2）提高患者外周血中明显降低的CD

、CD

水平

降低明显升高的CD

水平

使CD

/CD

比例达到平衡

从而维持T细胞免疫调节网络平衡。

Abstract

(%)

leading balance of CD4 and CD8For assessing clinical therapeutic effect of Du Su Qing on seline bacterial pneumonia （accumulation of phlegm and heat in the lung

deficiency of both Qi and Yin）

senile patients of pneumonia on the basis of routine treatment of Western medicines were randomly divided into treatment group （treated with Du Su Qing Oral Liquid） and control group （treated routinely with Western medicines）

and the healthy old people were used as healthy senile group. Changes of IgA

IgG

IgM

and CD3

CD4

CD8 and their ratio in the peripheral blood before and after treatment were investigated. Results indicated that of 33 cases in the treatment group

10 cases were cured

16 markdely effective

5 improved

the effective rate being 93. 93%; of 31 cases in the control group

corresponding fingers were 5

and 83. 87%

with a significant difference between the two groups in therapeutic effect. The levels of IgA

IgG

C3 and CD8 （%） in the senile patients of pneumonia were significantly higher than those in the healthy senile group

and after treatment they

except C4

in the treatment group were improved

which were superior to those in the control group. It is suggested that combination of Du Su Qing with routine treatment of Western medicines has a significant therapeutic effect and the mechanisms may be: （1） decreasing the increased IgA

IgG

IgM and C3 levels; （2） increasing the decreased CD3 （%） and CD4 （%）

decreasing the increased CD8

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