Clinical and Experimental Studies on Gan Bao Chong Ji Antagonising Hepatic Fibrosis in the Patient of Hepatitis B

doi:10.13288/j.11-2166/r.2001.07.021

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Clinical and Experimental Studies on Gan Bao Chong Ji Antagonising Hepatic Fibrosis in the Patient of Hepatitis B

更新时间：2021-11-20

- Clinical and Experimental Studies on Gan Bao Chong Ji Antagonising Hepatic Fibrosis in the Patient of Hepatitis B
- Journal of Traditional Chinese Medicine Issue 7, Pages: 415-417(2001)
- 作者机构：
  
  1. 中国人民解放军第四五四医院传染科
  2. 南京中医药大学南京市白下区马路街32号,210002
- 作者简介：
- 基金信息：
- DOI：10.13288/j.11-2166/r.2001.07.021
  CLC： R259.7
- Published：2001
- 稿件说明：
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[1]潘雪飞,张长法,刘英娜,邱蔚蔚,常洁,施斌斌,杜斌.肝宝冲剂抗乙型肝炎肝纤维化的临床及实验研究[J].中医杂志,2001(07):415-417+8.

Clinical and Experimental Studies on Gan Bao Chong Ji Antagonising Hepatic Fibrosis in the Patient of Hepatitis B[J]. Journal of Traditional Chinese Medicine2001, (7): 415-417.
[1]潘雪飞,张长法,刘英娜,邱蔚蔚,常洁,施斌斌,杜斌.肝宝冲剂抗乙型肝炎肝纤维化的临床及实验研究[J].中医杂志,2001(07):415-417+8. DOI： 10.13288/j.11-2166/r.2001.07.021.

Clinical and Experimental Studies on Gan Bao Chong Ji Antagonising Hepatic Fibrosis in the Patient of Hepatitis B[J]. Journal of Traditional Chinese Medicine2001, (7): 415-417. DOI： 10.13288/j.11-2166/r.2001.07.021.

摘要

为了研究肝宝冲剂治疗慢性乙型肝炎的临床效果及抗纤维化作用。我们进行了临床对照观察及抗大鼠肝纤维化实验。结果:肝宝冲剂治疗105例慢性乙型病毒性肝炎

总有效率为90.48％

对照组为78.57％

两组比较差异有显著性（P<0.05）。肝宝冲剂组丙氨酸转氨酶（ALT）复常率、复常时间、ALT稳定率及HBeAg、DNA转阴率均优于对照组。动物实验提示

肝宝冲剂有显著的抗大鼠肝脏纤维化作用。表明

肝宝冲剂治疗慢性乙型病毒性肝炎有较好的保肝降酶效果

并能改善肝脏纤维化。

Abstract

One hundred and five cases of chronic hepatitis B were treated with Gan Bao Chong Ji

with a total effective rate of 90. 48% and the effective rate in the control group was 78. 57%

with a significant difference between the two groups （P<0. 05）. The recovery normal rate

recovery normal time and the stable rate of alanine aminotransferase （ALT）

and HBeAg and DNA turning negative rate all were superior to those in the control group. Experiments in the animal indicated that Gan Bao Chong Ji had a significant action of antagonising hepatic fibrosis in rats. It is suggested that Gan Bao Chong Ji has a better effect of protecting the liver and decreasing ALT in treatment of chronic hepatitis B and can improve hepatic fibrosis.

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Department of Hepatic Diseases, Beijing Hospital of TCM

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