In order to explore the therapeutic action and mechanisms of Chang An Capsules for treatment of ulcerative colitis

62 cases were randomly divided into two groups and treated with oral administration of Chang An Capsules and Bu Pi Yi Chang Pill respectively

for 3 therapeutic courses. Clinical observation

pathological therapeutic effects

and changes of enteroscopic sign

serum immunoglobin

complement C3

serum superoxide dismutase （SOD） and lipid peroxide （LPO） before and after treatment were observed. Results indicated that in the treatment group

the total effective rate was 93. 80%

the therapeutic effects for enteroscopy and pathology were 81. 30% and 84. 40% respectively

and serum immunoglobin

complement Cs

serum superoxide dismutase （SOD） activity and lipid peroxide （LPO） were improved or inhibited

with significant difference compared with the control group （P < 0. 05 or P<0. 01）. It is suggested that Chang An Capsules has an obvious therapeutic action

and its mechanism is possibly related with inhibition of lesion of intestinal mucosa. promotion of ulcerative repair

strengthening of removing free radicals and anti ?oxidation abiliity

and regulation of immunological function.