Study on correlativity of blood physical and chemical properties with TCM syndrome types in the patient of coronary heart disease with blood stasis syndrome

doi:10.13288/j.11-2166/r.2002.05.043

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Study on correlativity of blood physical and chemical properties with TCM syndrome types in the patient of coronary heart disease with blood stasis syndrome

更新时间：2021-11-20

- Study on correlativity of blood physical and chemical properties with TCM syndrome types in the patient of coronary heart disease with blood stasis syndrome
- Journal of Traditional Chinese Medicine Issue 5, Pages: 378-379(2002)
- 作者机构：
  
  1. 中山医科大学附属第一医院
  2. 中山医科大学附属第一医院广州市中山二路58号,510080
- 作者简介：
- 基金信息：
- DOI：10.13288/j.11-2166/r.2002.05.043
  CLC： R259.4
- Published：2002
- 稿件说明：
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[1]丘瑞香,罗致强,朱雅宜,秦鉴.冠心病血瘀证血液理化特性与中医证型相关性研究[J].中医杂志,2002(05):378-379+5.

Study on correlativity of blood physical and chemical properties with TCM syndrome types in the patient of coronary heart disease with blood stasis syndrome[J]. Journal of Traditional Chinese Medicine2002, (5): 378-379.
[1]丘瑞香,罗致强,朱雅宜,秦鉴.冠心病血瘀证血液理化特性与中医证型相关性研究[J].中医杂志,2002(05):378-379+5. DOI： 10.13288/j.11-2166/r.2002.05.043.

Study on correlativity of blood physical and chemical properties with TCM syndrome types in the patient of coronary heart disease with blood stasis syndrome[J]. Journal of Traditional Chinese Medicine2002, (5): 378-379. DOI： 10.13288/j.11-2166/r.2002.05.043.

摘要

目的:探讨血瘀证的证型实质。方法:检测216例冠心病血瘀证患者高切速全血粘度（ηHB）、低切速全血粘度（ηLB）、血浆粘度（ηP）、红细胞聚集指数（AI）、红细胞压积（HCT）及血清总胆固醇（CH）、甘油三酯（TG）、血浆纤维蛋白原（Fb）、前列环素（PGI

）、血栓素（TXA

）的浓度。结果:气滞血瘀组ηLB、A显著升高

PGI

/TXA

明显下降

血液呈高聚状态;阴虚血瘀组CH、HCT、Fb、AI、ηLB明显增高

血液呈高浓、高凝、高聚状态;痰浊血瘀组ηLB、ηP、TG显著升高

血液里高粘状态;气虚血瘀组仅ηHB有所升高

其他指标变化不明显。结论:提示血瘀证的不同证型有不同的生化物质基础

血液理化特性变化与中医证型关系密切。为血瘀证进一步分型论治提供了实验依据。

Abstract

Objective: To probe into essence of syndrome types of blood stasis syndrome. Methods: High shearing whole blood viscosity （ηHB）. low shearing whole blood viscosity （ηLB）

plasma viscosity （ηP）

aggregation index of erythrocyte （AI）

hematocrit （HCT） and levels of serum total cholesterol （CH）

triglyceride （TG）

plasma fibrinogen （Fb）

prostacyclin （PGI2）

thromboxane （TXA2） were determined in 216 cases of coronary heart disease with blood stasis syndrome. Results: ηLB and AI increased and PGI2/TXA2 ratio decreased significantly in the group of stagnation of Qi and stasis of blood

showing high aggregation state of blood: CH

HCT

AI and ηLB increased significantly in the group of blood stasis due to Yin -deficiency

showing high concentration

high agglutination and high aggregation state of blood : ηLB

ηP and TG increased significantly in the group of stagnation of phlegm and blood

showing high viscosity state of blood; only ηHB had some increase in the group of Qi - deficiency and blood stasis . Conclusion: Different syndrome types of blood stasis syndromehave different biochemical material base

and changes of blood physical and chemical properties are closely related with TCM syndrome types

which provides an experimental basis for treatment of subtypes of blood stasis syndrome.

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