Effect of Shen Xian Kang Tang on expression of serum TGF-β1 in the patient of mesangial proliferative glomerulonephritis[J]. Journal of Traditional Chinese Medicine2002, (9): 673-674. DOI: 10.13288/j.11-2166/r.2002.09.027.
Effect of Shen Xian Kang Tang on expression of serum TGF-β1 in the patient of mesangial proliferative glomerulonephritis[J]. Journal of Traditional Chinese Medicine2002, (9): 673-674. DOI: 10.13288/j.11-2166/r.2002.09.027.DOI:
Effect of Shen Xian Kang Tang on expression of serum TGF-β1 in the patient of mesangial proliferative glomerulonephritis
Objective: To probe the inhibitory action of Shen Xian Kang Tang on serum transforming growth factor β1 (TGF - β1) in the patient of mesangial proliferative glomerulonephritis (MsPGN)
Methods: 60 cases of MsPGN were randomly divided into nephritis control group
benazepril group and Shen Xian Kang group
and the changes of serum TGF -β1 before and after treatment were investigated. Results: After treatment
serum TGF -β1 levels in the benazepril group and Shen Xian Kang group were significantly down - regulated (P<0. 01)
with no significant difference between the two groups (P>0. 05)
and there was significant difference as the two groups compared with the control group (P<0. 01). Conclusion: Shen Xian Kang Tang may have the action of anti - TGF - β1
being advantageous to delaying injury of the kidney.
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