Clinical observation on 96 cases of primary osteoporosis treated with Yi Shen Zhuang Gu Mixture

doi:10.13288/j.11-2166/r.2003.03.022

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Clinical observation on 96 cases of primary osteoporosis treated with Yi Shen Zhuang Gu Mixture

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- Clinical observation on 96 cases of primary osteoporosis treated with Yi Shen Zhuang Gu Mixture
- Journal of Traditional Chinese Medicine Issue 3, Pages: 188-190(2003)
- 作者机构：
  
  1. 首都医科大学宣武医院中医科
  2. 首都医科大学宣武医院中医科妇科、中心仪器室、药剂科北京市宣武区长椿街45号,100053
- 作者简介：
- 基金信息：
- DOI：10.13288/j.11-2166/r.2003.03.022
  CLC： R259.8
- Published：2003
- 稿件说明：
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[1]王明越,龚玲,夏蓓,曹俊卿,周佩卿,胡杰.益肾壮骨合剂治疗原发性骨质疏松症96例临床观察[J].中医杂志,2003(03):188-190+164.

Clinical observation on 96 cases of primary osteoporosis treated with Yi Shen Zhuang Gu Mixture[J]. Journal of Traditional Chinese Medicine2003, (3): 188-190.
[1]王明越,龚玲,夏蓓,曹俊卿,周佩卿,胡杰.益肾壮骨合剂治疗原发性骨质疏松症96例临床观察[J].中医杂志,2003(03):188-190+164. DOI： 10.13288/j.11-2166/r.2003.03.022.

Clinical observation on 96 cases of primary osteoporosis treated with Yi Shen Zhuang Gu Mixture[J]. Journal of Traditional Chinese Medicine2003, (3): 188-190. DOI： 10.13288/j.11-2166/r.2003.03.022.

摘要

目的:客观评价益肾壮骨合剂的疗效及安全性。方法:临床随机观察患有骨质疏松症的患者160例

其中治疗组（96例）给予益肾壮骨合剂

对照组（32例）给予肾骨胶囊

空白组（32例）为已诊断为骨质疏松症

但半年内未服任何药物的患者。观测骨密度（BMD）、临床症状、骨钙素（BGP）、尿吡啶酚（PYD）、雌二醇（E

）、睾酮（T）、尿素氮（BUN）、转氨酶、血尿常规。结果:治疗组的综合疗效明显优于对照组。结论:该中药安全可靠

能提高骨密度

促进骨形成和抑制骨吸收

从而起到治疗骨质疏松症的作用。

Abstract

Objective: To objectively assess the therapeutic effect and safety of Yi Shen Zhuang Gu Mixture. Methods: 160 cases of osteoporosis were observed. Among them

the treatment group （96 cases） were treated with Yi Shen Zhuang Gu Mixture and the control group （32 cases） were treated with Shen Gu Capsules and 32 cases of osteoporosis who had not taken any medicines in a half year were used as blank group. Bone density

clinical symptoms

osteocalcin

urinary pyridol

estrodiol

testosterone

urea nitrogen

transaminase. calcium

phosphorus

alkaline phosphatase

urine routine examinations were investigated. Results: The comprehensive therapeutic effect in the treatment group was better than that in the control group. Conclusion: Yi Shen Zhuang Gu Mixture can increase bone density

promote formation of bone and inhibit absorption of bone

and it is safe and reliable to treat osteoporosis.

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Related Institution

中国中医研究院基础理论研究所病理研究室

中国中医研究院基础理论研究所病理研究室北京市东直门内北新仓18号

首都医科大学宣武医院中心仪器室

首都医科大学宣武医院妇产科

首都医科大学宣武医院中药制剂室北京市宣武区长椿街45号

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