Study on Correlativity of TCM Phlehm and Stasis Coexistence Syndrome with Liver Fibrosis in the Patient of Chronic Virus Hepatitis

doi:10.13288/j.11-2166/r.2003.07.039

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Study on Correlativity of TCM Phlehm and Stasis Coexistence Syndrome with Liver Fibrosis in the Patient of Chronic Virus Hepatitis

更新时间：2021-11-22

- Study on Correlativity of TCM Phlehm and Stasis Coexistence Syndrome with Liver Fibrosis in the Patient of Chronic Virus Hepatitis
- Journal of Traditional Chinese Medicine Issue 7, Pages: 535-536(2003)
- 作者机构：
  
  1. 黑龙江省哈尔滨市传染病医院
  2. 黑龙江中医药大学附属第一医院
  3. 黑龙江省哈尔滨市传染病医院哈滨市香坊区公滨路309号,150030
- 作者简介：
- 基金信息：
- DOI：10.13288/j.11-2166/r.2003.07.039
  CLC： R259.1
- Published：2003
- 稿件说明：
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[1]陶翠玲,李延,赵艳波.慢性病毒性肝炎中医痰瘀互结证与肝纤维化的相关性研究[J].中医杂志,2003(07):535-536+5.

Study on Correlativity of TCM Phlehm and Stasis Coexistence Syndrome with Liver Fibrosis in the Patient of Chronic Virus Hepatitis[J]. Journal of Traditional Chinese Medicine2003, (7): 535-536.
[1]陶翠玲,李延,赵艳波.慢性病毒性肝炎中医痰瘀互结证与肝纤维化的相关性研究[J].中医杂志,2003(07):535-536+5. DOI： 10.13288/j.11-2166/r.2003.07.039.

Study on Correlativity of TCM Phlehm and Stasis Coexistence Syndrome with Liver Fibrosis in the Patient of Chronic Virus Hepatitis[J]. Journal of Traditional Chinese Medicine2003, (7): 535-536. DOI： 10.13288/j.11-2166/r.2003.07.039.

摘要

目的:通过对慢性病毒性肝炎181例的临床发病及病变过程进行研究

探讨其中医痰瘀互结证与肝纤维化血清透明质酸（HA）、层粘蛋白（LN）、三型前胶原（PCⅢ）之间的关系。方法:对病例进行证候分类

统计各证候出现的例数。同时运用放免法检测初诊患者肝纤维化的指标。结果:患者中涉及痰瘀互结证者64例

构成比占35.35％.其发生频数最高为312次

说明痰瘀互结证是慢性病毒性肝炎的常见证候

并且痰瘀证积分与血清HA、LN、PCⅢ水平及甘油三酯（TG）水平呈正相关（r=0.85、0.78、0.82、0.64）;TG与HA、LN、PCⅢ呈正相关（r=0.54、0.62、0.58）。结论:提示慢性病毒性肝炎中医痰瘀互结证与肝纤维化关系密切

为痰瘀互结可能是病毒性肝炎后肝纤维化中医病理实质之说提供了临床及实验依据。

Abstract

Objective: To explore relation of TCM phlehm and blood stasis coexistence syndrome of chronic virus hepatic disease with indexes of liver fibrosis. serum hyaluronic acid （HA）

laminin（LN） and type Ⅲ procollagen （PC Ⅲ ） levels. Methods: Syndromes were classfied and numbers of cases appearing the syndrome in 181 cases of chronic virus hepatitis were analysed

and the indexes of hepatic fibrosis were determined by radioimmunoassay. Results: 64 cases were involved in phlehm and blood stasis coexistence syndrome accounting for 35. 35% with the highest appearing frequency of 312 times

indicating that phlegm and blood stasis coexistence syndrome is a commonly-seen syndrome in chronic virus hepatitis. The cumulative scores of phlegm and blood stasis syndrome showed possitive correlation with serum HA. LN. PC Ⅲ and triglyceride（TG） levels （r = o. 85. 0.78. 0.82. 0. 64 respectively）. TG level was positively relative with HA

LN. PC Ⅲ levels （r = 0. 54. 0.62. 0. 58 respectively）. Conclusion: TCM phleghm and blood stasis coexistence syndrome of chronic virus hepatitis was closely related to liver fibrosis. which provides clinical and experimental basis for that phlehm and blood stasis coexistence is possibly TCM pathological essence of liver fibrosis after virus hepatitis.

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