Effect of Needling Method for Regulating Mental Activity and Tonifying the Kidney on Aromatizase Cytochrome P450 mRNA Expression in the Ovary of Climacteric Rats

doi:10.13288/j.11-2166/r.2003.08.017

您当前的位置：

首页 >

文章列表页 >

Effect of Needling Method for Regulating Mental Activity and Tonifying the Kidney on Aromatizase Cytochrome P450 mRNA Expression in the Ovary of Climacteric Rats

更新时间：2021-11-22

- Effect of Needling Method for Regulating Mental Activity and Tonifying the Kidney on Aromatizase Cytochrome P450 mRNA Expression in the Ovary of Climacteric Rats
- Journal of Traditional Chinese Medicine Issue 8, Pages: 589-591(2003)
- 作者机构：
  
  1. 安徽中医学院临床医学二系
  2. 天津中医学院第一附属医院
  3. 天津中医学院第一附属医院合肥市梅山路103号,230038
- 作者简介：
- 基金信息：
- DOI：10.13288/j.11-2166/r.2003.08.017
  CLC： R245
- Published：2003
- 稿件说明：
移动端阅览
[1]沈晓明,杜元灏,胡玲,石学敏.调神益肾针法对更年期大鼠卵巢芳香化酶细胞色素P450mRNA表达的影响[J].中医杂志,2003(08):589-591+5.

Effect of Needling Method for Regulating Mental Activity and Tonifying the Kidney on Aromatizase Cytochrome P450 mRNA Expression in the Ovary of Climacteric Rats[J]. Journal of Traditional Chinese Medicine2003, (8): 589-591.
[1]沈晓明,杜元灏,胡玲,石学敏.调神益肾针法对更年期大鼠卵巢芳香化酶细胞色素P450mRNA表达的影响[J].中医杂志,2003(08):589-591+5. DOI： 10.13288/j.11-2166/r.2003.08.017.

Effect of Needling Method for Regulating Mental Activity and Tonifying the Kidney on Aromatizase Cytochrome P450 mRNA Expression in the Ovary of Climacteric Rats[J]. Journal of Traditional Chinese Medicine2003, (8): 589-591. DOI： 10.13288/j.11-2166/r.2003.08.017.

摘要

目的:研究调神益肾针法对更年期大鼠卵巢芳香化醇细胞色素P450(P450

AROM

)mRNA表达的影响。方法:采用组织细胞原位杂交技术

辅以计算机图像分析。结果:更年期大鼠卵巢窦状卵泡、成熟黄体细胞中P450

AROM

mRNA的表达减弱

间质腺细胞中的表达则基本维持正常;经针刺干预后

这些部位尤其是窦状卵泡、成熟黄体该酶mRNA的表达明显增强。结论:促进卵巢P450

AROM

mRNA的表达

有利于增加雌激素合成限速酶的含量

这可能是调神益肾针法升高体内雌激素水平的分子机制之一。安徽中医学院临床医学二系

合肥市梅山路103号（230038）天津中医学院第一附属医院安徽中医学院临床医学二系.合肥市梅山路103号（230038）

Abstract

Objective: To study the effect of needling method for regulating mental activity and tonifying the kidney on expression of aroma-tizase cytochrome P450 （P450 arom） in climacteric rats. Methods: Hybridization in situ and computer-aided image analysis were adopted. Results: Expression of P450 arom mRNA in cells of sinusoidal follicles and the mature corpu luteum of the ovary decreased and in the interstitial adenocytes basically kept normal in climacteric rats. After acupuncture

expression of P450 arom mRNA in these parts particularly in the sinusoidal follicle and the mature corpus luteum were significantly strengthened. Conclusion: Promotion of expression of P450 arom mRNA in the ovary is beneficial to increase of the content of rate-limiting enzyme for synthesis of estrin. which is possibly one of molecular mechanisms of the needling method for regulating mental activity and tonifying the kidney increasing estrin level in the body.

关键词

Keywords

references

查看原文

Views

206

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

Effect of Xiaoqinglong Decoction （小青龙汤） on Th2 Immune Responses and Nasal Mucosal TSLP/OX40L Pathway in Allergic Rhinitis Model Rats

The Philosophy and Practical Pathway of "Dao （道）-Shen （神）-Formula" in Traditional Chinese Medicine

LI Guolie's Experience in Treating Orthostatic Hypotension from the Perspective of "Raising the Clear and Directing the Turbid Downward"

Exploration on the Connotation and Application of the Three Aspects of "Dietary Inquiry" for "Appetite" "Eating Capacity" "Food Preference"

Current Status and Strategic Recommendations for Randomized Controlled Trials on Functional Dyspepsia-Irritable Bowel Syndrome Comorbidity：from a Real-World Research Perspective

Related Author

No data

Related Institution

No data

Address：No.16, Nanxiao street, Dongzhimen, Dongcheng District, Beijing Postal code：100700
Tel：010-64035632 Email：jtcmcn@188.com
Technical support is provided by Beijing Founder electronics co., LTD 京ICP备09064830号-19 京公网安备11010102007558号
It is recommended to read the content of this site in Chrome&IE9+. Please switch to extreme mode in browser 360.
Cookies We use cookies to help provide and enhance our service and tailor content. By continuing, you agree to the use of cookies.

⁰