Objective: To observe the development of syndromes and characteristics of coexistant syndromes in the patient of hepatic cancer. Methods: 2060 cases of primary hepatic cancer were clinically researched by a large sample number clinical epidemiological survey program. Results: The pathogenesis of primary hepatic cancer is continuously changing with development of course of disease. From stage I to I

syndrome of stagnation of the liv-er-Qi and syndrome of deficiency of spleen-Qi are main. At stageI

stasis of blood in the liver

Qi-stagnation

Qi-deficiency and damp-heat are main. At stage III

Qi-deficierncy

Yin deficiency

blood stasis

Qi-stagnation and retention of water in the body are main. The occurrence rate of syndromes at various stages in the first fourth positions are Qi-stagnation

blood stasis

Qi-deficiency and Yin-deficiency. The patients with no syndrome able to differentiated only accounted for 1. 07%

with 3 syndrome groups for 23. 06%

4 syndromes for 24. 37%

5 syndromes for 18. 11%

averaging 3. 75 syndromes in each patient

and averaging 2. 03 syndrome-times at stage I

3. 47 at stageII

and 4. 99 at stage III . Conclusion: Coexistent syndromes were more obvious and pathogeneses were more complicated with development of condition of illness. Stagnation of Qi and stasis of blood

and deficiency of both Qi and Yin are basic pathogenesis

running through the course of the disease.