Effects of Ganzhikang Capsule on Ultrastructure Changes in Non-Alcoholic Fatty Liver Rats

doi:10.13288/j.11-2166/r.2004.03.038

您当前的位置：

首页 >

文章列表页 >

Effects of Ganzhikang Capsule on Ultrastructure Changes in Non-Alcoholic Fatty Liver Rats

更新时间：2021-11-20

- Effects of Ganzhikang Capsule on Ultrastructure Changes in Non-Alcoholic Fatty Liver Rats
- Journal of Traditional Chinese Medicine Issue 3, Pages: 220-221(2004)
- 作者机构：
  
  1. 湖北省中医院脏象肝病研究所
  2. 湖北中医学院武汉市武昌区花园山4号,430061
  3. 级研究生,2000
- 作者简介：
- 基金信息：
- DOI：10.13288/j.11-2166/r.2004.03.038
  CLC： R285
- Published：2004
- 稿件说明：
移动端阅览
[1]夏瑾瑜,贾学平,程良斌.肝脂康胶囊对大鼠非酒精性脂肪肝超微结构变化的影响[J].中医杂志,2004(03):220-221+223+5.

Effects of Ganzhikang Capsule on Ultrastructure Changes in Non-Alcoholic Fatty Liver Rats[J]. Journal of Traditional Chinese Medicine2004, (3): 220-221.
[1]夏瑾瑜,贾学平,程良斌.肝脂康胶囊对大鼠非酒精性脂肪肝超微结构变化的影响[J].中医杂志,2004(03):220-221+223+5. DOI： 10.13288/j.11-2166/r.2004.03.038.

Effects of Ganzhikang Capsule on Ultrastructure Changes in Non-Alcoholic Fatty Liver Rats[J]. Journal of Traditional Chinese Medicine2004, (3): 220-221. DOI： 10.13288/j.11-2166/r.2004.03.038.

摘要

目的:观察肝脂康胶囊对非酒精性脂肪肝动物模型超微结构变化的影响

为临床提供形态学依据。方法:采用高脂饮食造成脂肪肝动物模型

以东宝肝泰作对照

观察模型大鼠肝组织超微结构的变化。结果:高脂饲料模型组大鼠肝细胞脂变严重

出现炎症浸润、变性、坏死

电镜可见线粒体变形、肿胀

内质网扩张等超微结构变化。治疗后

肝脂康治疗组肝细胞超微结构有显著恢复

脂变程度明显减轻。同时病理观察结果显示

在使大鼠脂肪变性恢复正常方面

肝脂康胶囊优于东宝肝泰（P<0.05）。结论:形态学观察证实肝脂康胶囊对非酒精性脂肪肝有效。

Abstract

Objective: To observe effects of Ganzhikang Capsule on ultrastructures in non-alcoholic fatty liver model rats so as to provide morphological basis for clinical treatment. Methods: Fatty liver model rats were induced by high fat diet

and the effects of Ganzhikang Capsule on microstructures in liver tissue were investigated with Dong Bao Gan Tai used as control medicine. Results: In the model group

serious fatty degeneration of hepatocytes with inflammatory infiltration

degeneration and necrosis

and deforming

swelling of mitochondrion

dilatation of endoplasmic reticulum were found. After treatment of Ganzhikang Capsule

microstructures of hepatocytes restored obviously

fatty degeneration relieved significantly

and Ganzhikang Capsule was superior to Dong Bao Gan Tai in restoration of fatty degeneration （P < 0. 05）. Conclusion: Ganzhikang Capsule is effective for non-alcoholic fatty liver.

关键词

Keywords

references

查看原文

Views

124

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

Clinical observation on 102 cases of alcoholic fatty liver treated with Juge Yigan Decoction

Current Status and Strategic Recommendations for Randomized Controlled Trials on Functional Dyspepsia-Irritable Bowel Syndrome Comorbidity：from a Real-World Research Perspective

LI Guolie's Experience in Treating Orthostatic Hypotension from the Perspective of "Raising the Clear and Directing the Turbid Downward"

WANG Qingguo's Experience in Treatment of Headache Based on the Concept of "Achieving Harmony by Unblocking and Balancing"

Exploring the Comorbidity Mechanism，Prevention and Treatment Strategies of Rheumatoid Arthritis with Coronary Atherosclerotic Heart Disease Based on Collateral Disease Theory

Related Author

Jia Jingpeng. Jiang SenFirst People’s Hospital of Yaodu District. Linfen City. Shanxi Province. Shanxi 041000

蒋森

Related Institution

山西省临汾市尧都区第一人民医院肝病科

山西省临汾市尧都区第一人民医院肝病科临汾市古楼南马尾巷16号

Address：No.16, Nanxiao street, Dongzhimen, Dongcheng District, Beijing Postal code：100700
Tel：010-64035632 Email：jtcmcn@188.com
Technical support is provided by Beijing Founder electronics co., LTD 京ICP备09064830号-19 京公网安备11010102007558号
It is recommended to read the content of this site in Chrome&IE9+. Please switch to extreme mode in browser 360.
Cookies We use cookies to help provide and enhance our service and tailor content. By continuing, you agree to the use of cookies.

⁰