Study on Correlativity of TCM Syndrome Types of Primary Infertility with Levels of Sexual Hormones

doi:10.13288/j.11-2166/r.2005.03.033

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Study on Correlativity of TCM Syndrome Types of Primary Infertility with Levels of Sexual Hormones

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- Study on Correlativity of TCM Syndrome Types of Primary Infertility with Levels of Sexual Hormones
- Journal of Traditional Chinese Medicine Issue 3, Pages: 220-222(2005)
- 作者机构：
  
  1. 福建中医学院中医系
  2. 福建省厦门市中西医结合医院
  3. 福建省漳州市中医院
  4. 福建中医学院中医系福州市五四路282号,350003
- 作者简介：
- 基金信息：
- DOI：10.13288/j.11-2166/r.2005.03.033
  CLC： R271.14
- Published：2005
- 稿件说明：
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[1]李灿东,高碧珍,兰启防,黄熙理,林雪娟,丁杰.原发性不孕症中医辨证分型与性激素水平的相关性研究[J].中医杂志,2005(03):220-222.

Study on Correlativity of TCM Syndrome Types of Primary Infertility with Levels of Sexual Hormones[J]. Journal of Traditional Chinese Medicine2005, (3): 220-222.
[1]李灿东,高碧珍,兰启防,黄熙理,林雪娟,丁杰.原发性不孕症中医辨证分型与性激素水平的相关性研究[J].中医杂志,2005(03):220-222. DOI： 10.13288/j.11-2166/r.2005.03.033.

Study on Correlativity of TCM Syndrome Types of Primary Infertility with Levels of Sexual Hormones[J]. Journal of Traditional Chinese Medicine2005, (3): 220-222. DOI： 10.13288/j.11-2166/r.2005.03.033.

摘要

目的:探讨不孕症证候规律及其与性激素的相关性。方法:选择原发性不孕症患者70例

健康对照者19例

以辨证分型、证候积分、性激素检测为指标。结果:不孕症以兼夹证多见

其中肝郁证、肾虚证所占比例为高（P

0.01）。月经周期第10天

各证型组雌二醇（E

）均显著高于对照组（P

0.05或 P

0.01）;肝郁组、肾虚组孕酮（P）显著高于对照组（P

0.01）;肝郁组、痰湿组、血瘀组泌乳素（PRL）均显著高于对照组（P

0.05或 P

0.01）。月经周期第20天

肝郁组、肾虚组、痰湿组 P 显著低于对照组（P

0.01）;不同证型组 P/E

均显著低于对照组（P

0.05或P

0.01）;痰湿组 E

显著高于对照组（P

0.01）。结论:不孕症证候与性激素变化具有相关性

肝郁和肾虚是不孕症的基本证候和原发病机。

Abstract

Objective:To probe into correlativity of the syndrome law of infertility and its correlativity with sexual hormones.Methods: Seventy cases of primary infertility and 19 healthy women were selected

and TCM syndrome types

cumulative score of syndrome

sexual hormone levels were used as indexes.Results:Intermingling syndromes were commonly seen for infertility

among them

stagnation of the liver-Qi and kidney-deficiency syndromes had higher proportion（P

0.01）.At the tenth day of menstrual cycle

estradiol（E

）level in various syndrome types group was significantly higher than that of the control group（P

0. 05 or P

0.01）;progesterone（P）level in the group of stagnation of liver-Qi and the kidney deficiency group was significantly higher than that of the control group（P

0.01）

and prolactin（PRL）level in the group of stagnation of liver-Qi

the phlegm- dampness group and the blood stasis group was higher than that in the control group（P

0.05 or P

0.01）.At the 20th day of menstrual cycle

P level in the group of stagnation of liver-Qi

the kidney deficiency group and the phlegm-dampness group was significantly lower than that in the control group（P

0.01）;P/E

ratio in the different types groups was significantly lower than that in the control group（P

0.05 or P

0.01）;E

level in the phlegm-dampness group was significantly higher than that in the control group（P

0.05）.Conclusion:Syndromes of infertility are related with changes of sexual hormones

and stagnation of liver-Qi and kidney deficiency are basic syndromes and primary pathogenesis.

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