Effect of TCM Compound Preparation on Endothelium-Dependent Dilation of Brachial Artery in the Patient of Type Ⅱ Diabetes Mellitus

doi:10.13288/j.11-2166/r.2005.05.016

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Effect of TCM Compound Preparation on Endothelium-Dependent Dilation of Brachial Artery in the Patient of Type Ⅱ Diabetes Mellitus

更新时间：2021-11-20

- Effect of TCM Compound Preparation on Endothelium-Dependent Dilation of Brachial Artery in the Patient of Type Ⅱ Diabetes Mellitus
- Journal of Traditional Chinese Medicine Issue 5, Pages: 357-358(2005)
- 作者机构：
  
  1. 广东省深圳市宝安区西乡人民医院B超室
  2. 四川大学华西医院心内科
  3. 广东省深圳市宝安区西乡人民医院B超室深圳市宝安区西乡镇乐园街60号,518102
  4. 内分泌科
- 作者简介：
- 基金信息：
- DOI：10.13288/j.11-2166/r.2005.05.016
  CLC： R259
- Published：2005
- 稿件说明：
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[1]郭津含,唐红,陆志明,余叶蓉.中药复方制剂对2型糖尿病患者肱动脉血管内皮功能的影响[J].中医杂志,2005(05):357-358.

Effect of TCM Compound Preparation on Endothelium-Dependent Dilation of Brachial Artery in the Patient of Type Ⅱ Diabetes Mellitus[J]. Journal of Traditional Chinese Medicine2005, (5): 357-358.
[1]郭津含,唐红,陆志明,余叶蓉.中药复方制剂对2型糖尿病患者肱动脉血管内皮功能的影响[J].中医杂志,2005(05):357-358. DOI： 10.13288/j.11-2166/r.2005.05.016.

Effect of TCM Compound Preparation on Endothelium-Dependent Dilation of Brachial Artery in the Patient of Type Ⅱ Diabetes Mellitus[J]. Journal of Traditional Chinese Medicine2005, (5): 357-358. DOI： 10.13288/j.11-2166/r.2005.05.016.

摘要

目的:用高频超声评价中药复方制剂对2型糖尿病（DM）患者血管内皮功能（EDD）的改善作用。方法:以黄芪、川芎小复方制剂治疗2型糖尿病患者21例

疗程6个月;采用高频超声分别检测基础状态（D

）、反应性充血状态（D

）、含服硝酸甘油3～5分钟时（D

）肱动脉内径的变化。结果:2型糖尿病患者肱动脉血流介导的 EDD 中药治疗后较治疗前明显改善（P

0.01）;治疗前后肱动脉对硝酸甘油的反应无变化（P

0.05）。结论:中药复方制剂能有效改善2型糖尿病患者的 EDD;高频超声可用于2型糖尿病患者的 EDD 检测及药物疗效的评估。

Abstract

Objective:To observe the improving action of TCM compound preparation on endothelium-dependent dilation（EDD）in the patient of type Ⅱ diabetes mellitus（DM）.Methods:21 cases of type Ⅱ DM were treated with a small compound preparation composed of Radix Astragali and Rhizoma Chuanxiong for 6 courses

and changes of the diameter of brachial artery at basal state

reactive hyperemia and taking nitroglycerin for 3～5 mins were observed by high frequency ultrasonography.Results:After treatment of the TCM compound preparation

EDD mediated by blood flow of brachial artery in the patient of type Ⅱ DM improved significantly（P<0.01）

and after treatment of nitroglycerin EDD did not change（P>0.05）.Conclusion:TCM compound preparation can effectively improve EDD of the patient of type Ⅱ DM

and high frequency ultrasonography can be used for detection of EDD and assessment of therapeutic effect of drugs for the patient of type Ⅱ DM.

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