Effects of Yangxin Tongmai Tablet on Correlative Indexes of Insulin Resistance Syndrome

Yuan Zhaokai Huang Xianping Lu Fangguo

doi:10.13288/j.11-2166/r.2005.06.022

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Effects of Yangxin Tongmai Tablet on Correlative Indexes of Insulin Resistance Syndrome

更新时间：2021-11-20

- Effects of Yangxin Tongmai Tablet on Correlative Indexes of Insulin Resistance Syndrome
- Journal of Traditional Chinese Medicine Issue 6, Pages: 427-429(2005)
- 作者机构：
  
  1. 湖南中医学院中医诊断研究所
  2. 长沙冶金研究设计院职工医院
  3. 湖南中医学院中医诊断研究所湖南省长沙市韶山中路113号,410007
- 作者简介：
- 基金信息：
- DOI：10.13288/j.11-2166/r.2005.06.022
  CLC： R259
- Published：2005
- 稿件说明：
移动端阅览
[1]袁肇凯,黄献平,卢芳国,胡志希,谢梦洲,姚湘玲,王东生.养心通脉片对胰岛素抵抗综合征患者相关指标的影响[J].中医杂志,2005(06):427-429.

Yuan Zhaokai Huang Xianping Lu Fangguo. Effects of Yangxin Tongmai Tablet on Correlative Indexes of Insulin Resistance Syndrome[J]. Journal of Traditional Chinese Medicine2005, (6): 427-429.
[1]袁肇凯,黄献平,卢芳国,胡志希,谢梦洲,姚湘玲,王东生.养心通脉片对胰岛素抵抗综合征患者相关指标的影响[J].中医杂志,2005(06):427-429. DOI： 10.13288/j.11-2166/r.2005.06.022.

Yuan Zhaokai Huang Xianping Lu Fangguo. Effects of Yangxin Tongmai Tablet on Correlative Indexes of Insulin Resistance Syndrome[J]. Journal of Traditional Chinese Medicine2005, (6): 427-429. DOI： 10.13288/j.11-2166/r.2005.06.022.

摘要

目的:研究养心通脉片对胰岛素抵抗综合征（IRS）相关指标的影响。方法:将67例胰岛素抵抗综合征患者随机分为养心通脉片组（治疗组）33例和二甲双胍片组（对照组）34例

均治疗8周

观察比较两组治疗前后血葡萄糖（FPG）、血胰岛素（FINS）、胰岛素敏感指数（ISI）、胰岛素抵抗指数（IRI）、胰岛β细胞功能指数（HBCI）、血清总胆固醇（TC）、血清甘油三酯（TG）、高密度脂蛋白胆固醇（HDL-C）、低密度脂蛋白胆固醇（LDL-C）、收缩压（SBP）、舒张压（DBP）、体重指数（BMI）的变化。结果:治疗后两组 IRS 患者的 FPG、FINS、IRI、TC、TG、LDL-C、SBP、DBP、BIM 及临床症状积分等均明显降低

ISI 和 HDL-C均显著升高（P<0.05或 P<0.01）;而治疗组在提高 HBCI、降低 TG 的幅度等方面都显著优于对照组。结论:养心通脉片能有效地改善胰岛素敏感性

提高胰岛β细胞功能

促进组织摄取利用葡萄糖

改善脂质代谢

从而达到治疗 IRS 的目的。

Abstract

Objective:To observe effects of Yangxin Tongmai Tablet on correlative indexes of insulin resistance syndrome.Methods:67 cases of insulin resistance syndrome were randomly divided into treatment group（Yangxin Tongmai Tablet group

n=33）and control group（dimethyldiguanide group

n=34）.They were treated for 8 weeks.Changes of blood glucose（FPG）

insulin（FINS）

insulin sensitive index（ISI）

insulin resistance index（IRI）

islet β cell function index（HBCI）

serum total cholesterol（TC）

serum triglyceride（TG）

high density lipoprotein-cholesterol（HDL-C）

low density lipoprotein-cholesterol（LDL-C）

systolic pressure （SBP）

diastolic pressure（DBP）and body mass index（BMI）before and after treatment were observed.Results:After treatment

FPG

FINS

IRI

LDL-C

SBP

DBP

BMI and clinical symptom scores decreased

and ISI and HDL-C increased significantly in two groups（P<0.05 or P<0.01）;while the treatment group in increasing HBCI and decreasing TG was superior to the control group.Conclusion:Yangxin Tongmai Tablet can effectively improve insulin resistance

increase islet β-cell function

promote tissues up-taking and using glucose and improve metabolism of lipids.

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