Objective:To explore the therapeutic effect of Chinese herbal medicine for prevention and treatment of acute radiation oropharyngeal inflammation of nasopharyngeal carcinoma.Methods:120 cases of nasopharyngeal carcinoma were randomly divided into an experiment group of 60 cases treated with Chinese herbal medicine and a control group of 60 cases with gargling of Dobell’s solution.The incidence rate and the extent of radiation oropharyngeal inflammation

total therapeutic time and short-term therapeutic effect in both groups were investigated.Results:There was no oropharyngeal inflammation of grade 0 in both groups. The incidence rate of radiation oropharyngeal inflammation in the experiment group was significantly lower and the effective rate was significantly higher than those in the control group（P<0.05

P<0.01）;The total therapeutic time was（48.78±2.03） days in the experiment group and（52.43±3.18）days in the control group with a significant difference between the two groups （P<0.01）;The short-term therapeutic effect was CR88.33%

PR26.67% in the experiment group and CR81.67%

PR 30. 00% in the control group with no significant difference between the two groups（P>0.05）.Conclusion:Chinese herbal medicine combined with radiotherapy can relieve acute radiotherapy oropharyngeal inflammation in the patient of nasopharyngeal carcinoma with no significant adverse reaction and do not influence the short-term therapeutic effect.