Clinical Study on Qidan Granule for Treatment of 105 Cases of Pulmonary Interstitial Fibrosis

Jin Changjun Xin Hongtao Lin Dianjie

doi:10.13288/j.11-2166/r.2005.08.024

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Clinical Study on Qidan Granule for Treatment of 105 Cases of Pulmonary Interstitial Fibrosis

更新时间：2021-11-20

- Clinical Study on Qidan Granule for Treatment of 105 Cases of Pulmonary Interstitial Fibrosis
- Journal of Traditional Chinese Medicine Issue 8, Pages: 595-597(2005)
- 作者机构：
  
  1. 山东大学山东省立医院呼吸内科
  2. 山东省乐陵市人民医院山东省济南市经五路纬七路324号,250021
- 作者简介：
- 基金信息：
- DOI：10.13288/j.11-2166/r.2005.08.024
  CLC： R259
- Published：2005
- 稿件说明：
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[1]靳长俊,辛洪涛,林殿杰,高桂新,张华楠,王贞.芪丹颗粒剂治疗肺间质纤维化105例临床研究[J].中医杂志,2005(08):595-597.

Jin Changjun Xin Hongtao Lin Dianjie. Clinical Study on Qidan Granule for Treatment of 105 Cases of Pulmonary Interstitial Fibrosis[J]. Journal of Traditional Chinese Medicine2005, (8): 595-597.
[1]靳长俊,辛洪涛,林殿杰,高桂新,张华楠,王贞.芪丹颗粒剂治疗肺间质纤维化105例临床研究[J].中医杂志,2005(08):595-597. DOI： 10.13288/j.11-2166/r.2005.08.024.

Jin Changjun Xin Hongtao Lin Dianjie. Clinical Study on Qidan Granule for Treatment of 105 Cases of Pulmonary Interstitial Fibrosis[J]. Journal of Traditional Chinese Medicine2005, (8): 595-597. DOI： 10.13288/j.11-2166/r.2005.08.024.

摘要

目的:观察芪丹颗粒剂对肺间质纤维化患者的临床疗效。方法:选择105例肺间质纤维化患者作为治疗组

给予芪丹颗粒剂

对照组60例

给予强的松0.5mg/kg.两组疗程均为3～6个月

每1～3个月随诊1次。观察两组患者治疗后的症状、体征、肺部高分辨率 CT（HRCT）及肺功能变化。结果:治疗6个月后

治疗组症状、体征改善率优于对照组（P<0.05或 P<0.01）;治疗组治疗3个月和6个月后

肺 HRCT 和肺功能改善率优于对照组（P<0.05或 P<0.01）。结论:芪丹颗粒剂可以不同程度地改善肺间质纤维化患者症状和体征

使患者肺功能停止恶化

且用药期间未见任何副作用

耐受性良好。

Abstract

Objective:To investigate clinical therapeutic effect of Qidan Granule on pulmonary interstitial fibrosis（PIF）.Methods:The treatment group（105 cases）were treated by Qidan Granule

3 times a day

and the control group（60 cases）were treated by prednisone

0.5mg/kg

for 3～6 months.The patients were followed up once every 1～3 months.Changes of symptoms

signs and high-resolution computed tomogram（HRCT）and pulmonary function were investigated after treatment.Results:After treatment of 6 months

the improvement rate of symptoms and signs in the treatment group was superior to that in the control group（P<0. 05 or P<0.01）;After treatment for 3 or 6 months

the improvement rates of HRCT and the pulmonary function in the treatment group were better than those in the control group（P<0.05 or P<0.01）.Conclusion:Qidan Granule can improve symptoms and signs of the patient with pulmonary interstitial fibrosis in varying degrees and stop exacerbation of pulmonary function with no adverse effect.

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