Effects of Sanbaoxin on Formation of Thrombosis In Vivo and In Vitro in Rats

Gao Huili Wang Yuying Li Yikui

doi:10.13288/j.11-2166/r.2005.08.039

您当前的位置：

首页 >

文章列表页 >

Effects of Sanbaoxin on Formation of Thrombosis In Vivo and In Vitro in Rats

更新时间：2021-11-20

- Effects of Sanbaoxin on Formation of Thrombosis In Vivo and In Vitro in Rats
- Journal of Traditional Chinese Medicine Issue 8, Pages: 622-623(2005)
- 作者机构：
  
  1. 北京中医药大学基础医学部
  2. 中国中医研究院西苑医院
  3. 中国中医研究院西苑医院北京市朝阳区北三环东路11号,100029
- 作者简介：
- 基金信息：
- DOI：10.13288/j.11-2166/r.2005.08.039
  CLC： R285.5
- Published：2005
- 稿件说明：
移动端阅览
[1]高会丽,王玉英,李贻奎,宁可永,李连达.三保心对大鼠体内外血栓形成的影响[J].中医杂志,2005(08):622-623.

Gao Huili Wang Yuying Li Yikui. Effects of Sanbaoxin on Formation of Thrombosis In Vivo and In Vitro in Rats[J]. Journal of Traditional Chinese Medicine2005, (8): 622-623.
[1]高会丽,王玉英,李贻奎,宁可永,李连达.三保心对大鼠体内外血栓形成的影响[J].中医杂志,2005(08):622-623. DOI： 10.13288/j.11-2166/r.2005.08.039.

Gao Huili Wang Yuying Li Yikui. Effects of Sanbaoxin on Formation of Thrombosis In Vivo and In Vitro in Rats[J]. Journal of Traditional Chinese Medicine2005, (8): 622-623. DOI： 10.13288/j.11-2166/r.2005.08.039.

摘要

目的:观察三保心对大鼠体内外血栓形成的影响。方法:大鼠灌服三保心高、中、低3种剂量（10g 生药/kg、5g 生药/kg、1g 生药/kg）后

采用 Chandler 法造成体外血栓和电刺激颈总动脉形成体内血栓

观察三保心对体内外血栓形成的影响。结果:三保心高剂量组明显延长大鼠体内血栓形成时间（P<0.05）;高、中、低各剂量组均能显著抑制大鼠体外血栓的形成

使血栓长度明显缩短

血栓湿重和干重明显减轻（P<0.05或 P<0.01）。结论:提示三保心具有抑制血栓形成的作用。

Abstract

Objective:To observe effects of Sanbaoxin on formation of thrombosis in vivo and in vitro in rats.Methods:After the rats were administrated by high

mid and low doses

10g crude drug/kg

5g/kg and 1g/kg

respectively

Chandler method was used to form in vitro thrombosis and electrical stimulation of common carotid artery was used to form in vivo thrombosis

and then effects of Sanbaoxin on formation of thrombosis were observed.Results:The high dosage of Sanbaoxin could significantly prolongate the period of in vivo thrombosis（P<0.05）;the high

mid and low doses all could significantly inhibit in vitro thrombosis

significantly shortening the length of thrombus（P<0.01）

reducing wet weight and dry weight of thrombus（P<0.05）.Conclusion: Sanbaoxin has inhibiting action on thrombosis.

关键词

Keywords

references

查看原文

Views

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

Exploration on the Connotation and Application of the Three Aspects of "Dietary Inquiry" for "Appetite" "Eating Capacity" "Food Preference"

Current Status and Strategic Recommendations for Randomized Controlled Trials on Functional Dyspepsia-Irritable Bowel Syndrome Comorbidity：from a Real-World Research Perspective

Effect of Xiaoqinglong Decoction （小青龙汤） on Th2 Immune Responses and Nasal Mucosal TSLP/OX40L Pathway in Allergic Rhinitis Model Rats

The Philosophy and Practical Pathway of "Dao （道）-Shen （神）-Formula" in Traditional Chinese Medicine

Construction and Application of a Real-World Cohort of Community-Acquired Pneumonia Based on a Multimodal Large-Scale Traditional Chinese Medicine Big Data Platform

Related Author

No data

Related Institution

No data

Address：No.16, Nanxiao street, Dongzhimen, Dongcheng District, Beijing Postal code：100700
Tel：010-64035632 Email：jtcmcn@188.com
Technical support is provided by Beijing Founder electronics co., LTD 京ICP备09064830号-19 京公网安备11010102007558号
It is recommended to read the content of this site in Chrome&IE9+. Please switch to extreme mode in browser 360.
Cookies We use cookies to help provide and enhance our service and tailor content. By continuing, you agree to the use of cookies.

⁰