Clinical Study on Ruanjian Yiqi Huoxue Recipe for Treatment of 40 Cases of Ischemic Apoplexy

Wang Yuyong

doi:10.13288/j.11-2166/r.2005.11.018

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Clinical Study on Ruanjian Yiqi Huoxue Recipe for Treatment of 40 Cases of Ischemic Apoplexy

更新时间：2021-11-20

- Clinical Study on Ruanjian Yiqi Huoxue Recipe for Treatment of 40 Cases of Ischemic Apoplexy
- Journal of Traditional Chinese Medicine Issue 11, Pages: 832-834(2005)
- 作者机构：
  
  1. 山东大学山东省立医院中医科
  2. 山东大学山东省立医院中医科济南市经五纬七路324号,250021
- 作者简介：
- 基金信息：
- DOI：10.13288/j.11-2166/r.2005.11.018
  CLC： R255.2
- Published：2005
- 稿件说明：
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[1]王玉勇,郑建堂.软坚益气活血方治疗缺血中风40例临床研究[J].中医杂志,2005(11):832-834.

Wang Yuyong. Clinical Study on Ruanjian Yiqi Huoxue Recipe for Treatment of 40 Cases of Ischemic Apoplexy[J]. Journal of Traditional Chinese Medicine2005, (11): 832-834.
[1]王玉勇,郑建堂.软坚益气活血方治疗缺血中风40例临床研究[J].中医杂志,2005(11):832-834. DOI： 10.13288/j.11-2166/r.2005.11.018.

Wang Yuyong. Clinical Study on Ruanjian Yiqi Huoxue Recipe for Treatment of 40 Cases of Ischemic Apoplexy[J]. Journal of Traditional Chinese Medicine2005, (11): 832-834. DOI： 10.13288/j.11-2166/r.2005.11.018.

摘要

目的:探讨软坚益气活血方治疗缺血中风的临床疗效与机制。方法:80例患者随机分为治疗组和对照组

对治疗前后神经功能缺损程度评分、临床疗效、生活质量、外周血组织型纤溶酶原激活剂（t-PA）及组织型纤溶酶原激活剂抑制剂-1（PAI-1）的含量变化、血脂异常改善程度、血压的变化进行比较。结果:治疗组临床总有效率85%

对照组65%;治疗组冲经功能缺损程度评分、生活质量治疗后均有明显改善（P<0.01）;治疗后 t-PA 含量升高

PAI-1含量下降（P<0.01）;调血脂、降血压的效果优于对照组（P<0.01）。结论:软坚益气活血方具有调血脂、降血压、抗动脉硬化作用

通过调节 t-PA、PAI-1的含量与活性从而溶解血栓及预防新的血栓形成。

Abstract

Objective:To explore the clinical therapeutic effect and the mechanism of Ruanjian Yiqi Huoxue Recipe for treatment of ischemic apoplexy.Methods:80 cases were randomly divided into a treatment group and a control group.Scores of neurologic deficit

clinical therapeutic effects

quality of life

level of tissue plasminogen activator（t-PA）and plasminogen activator inhibitor-1（PAI-1）in the peripheral blood

improvement of abnormal blood lipids and blood pressure were observed before and after treatment.Results: Total effective rate in the treatment group was 85% and 65% in the control group.The score of neurologic deficit and quality of life in the treatment group improved significantly（P<0.01）.t-PA content increased and PAI-1 content decreased（P<0.01）. The treatment group was better than the control group in regulating blood lipids and decreasing blood pressure.Conclusion: Ruanjian Yiqi Huoxue Recipe has functions of adjusting abnormal blood lipids

decreasing blood pressure and anti-arteriosclerosis

and can regulate t-PA、PAI-1 to promote thromblosis and prevent formation of new thrombus.

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