Objective:To observe the therapeutic effect of integration of Chinese medicine with western medicine combined with endoscopy on ulcerative colitis.Methods:126 cases of ulcerative colitis were treated with oral administration of Chinese drugs for strengthening the spleen and supplementing qi

clearing away heat and toxic materials

and removing blood stasis and dredging the collaterals.Patients with the lesion in the left colic were given retention-enema of Chinese medicine

and severe patients were given oral administration of Etiasa or Azulfidine

3-4g each day.For the patient accompanied with inflammatory polyp

microwave coagulation or hot biopsy forceps was adopted for removing the polyp.Results:Among the 126 cases

98 cases were clinically cured

11 cases markedly effective

15 cases effective and 2 cases ineffective

the cured rate being 77.8% and the total effective rate being 86.5%.There was a significant difference before and after treatment in the cumulative score for main symptoms and lesion of intestinal mucosa（P<0.01）.For the patient who was treated by addition with endoscopy

the enteritical polyp disappeared completely.Conclusion:The integration of Chinese medicine with western medicine combined with endoscopy has obvious therapeutic effect on ulcerative colitis.