Objective:To observe the ratio of the syndrome of deficiency in origin to the syndrome of excess in superficiality in chronic renal failure（CRF）and co-existent states

and to analyze the relationship between TCM syndrome types and related biochemical indexes.Methods:TCM syndrome differentiation was carried out and related biochemical indexes were determined in 146 cases of CRF.The data were compared and analyzed with single factor analysis of variance between groups.Results:（1）Deficiency of both qi and yin of spleen and kidney was the most frequently-appeared type in the deficiency syndrome

and damp-heat syndrome was the most frequently-appeared type in the excess syndrome;（2）Serum creatinine（SCr）and blood uria nitrogen（BUN）in the patient of damp-turbid syndrome in the excess syndrome were significantly higher than those in the patient of damp-heat and blood stasis syndrome;（3）Fibrin in the patient of blood stasis was significantly higher than that in damp-heat syndrome and damp-turbid syndrome.Conclusion:Generation and development of CRF are closely related with dampness syndrome

usually marked by syndrome of damp-turbid

damp-heat

blood stasis

damp-stagnation

and was mainly related with abnormal renal function and hemorheologic indexes in the biochemical indexes.