Clinical Study on Bushen Qiangdu Recipe for Treatment of 259 Cases of Ankylosing Spondylitis

Wang Jianming; Yan Xiaoping; Wang Hao; et al.

doi:10.13288/j.11-2166/r.2006.06.026

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Clinical Study on Bushen Qiangdu Recipe for Treatment of 259 Cases of Ankylosing Spondylitis

更新时间：2021-11-17

- Clinical Study on Bushen Qiangdu Recipe for Treatment of 259 Cases of Ankylosing Spondylitis
- Journal of Traditional Chinese Medicine Issue 6, Pages: 433-435(2006)
- 作者机构：
  
  1. 中日友好医院中医风湿病科
  2. 中日友好医院中医风湿病科北京市朝阳区和平里樱花东街2号,100029
- 作者简介：
- 基金信息：
- DOI：10.13288/j.11-2166/r.2006.06.026
  CLC： R259
- Published：2006
- 稿件说明：
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[1]王建明,阎小萍,王昊,罗薇,马骁.补肾强督方治疗强直性脊柱炎患者259例临床研究[J].中医杂志,2006(06):433-435.

Wang Jianming, Yan Xiaoping, Wang Hao, et al. Clinical Study on Bushen Qiangdu Recipe for Treatment of 259 Cases of Ankylosing Spondylitis[J]. Journal of Traditional Chinese Medicine2006, (6): 433-435.
[1]王建明,阎小萍,王昊,罗薇,马骁.补肾强督方治疗强直性脊柱炎患者259例临床研究[J].中医杂志,2006(06):433-435. DOI： 10.13288/j.11-2166/r.2006.06.026.

Wang Jianming, Yan Xiaoping, Wang Hao, et al. Clinical Study on Bushen Qiangdu Recipe for Treatment of 259 Cases of Ankylosing Spondylitis[J]. Journal of Traditional Chinese Medicine2006, (6): 433-435. DOI： 10.13288/j.11-2166/r.2006.06.026.

摘要

目的探讨补肾强督方治疗强直性脊柱炎（AS）的临床疗效与安全性。方法本研究共入选259例门诊和住院患者

予补肾强督方治疗

每日1剂

早晚分服

疗程6个月

治疗前后评价如下疗效指标患者健康综合评分（BAS-G）、疾病活动指数（BASDAI）、功能指数（BASFI）、全身痛Likert四级评分、脊柱痛Likert四级评分、晨僵时间、医生总体评价、枕墙距、指地距、颌柄距、胸廓活动度、Schober征、脊柱活动度、“4”字试验、血沉（ESR）、C反应蛋白（CRP）

并观察血常规、尿常规、肝肾功能等药物安全性指标。结果259例患者经用补肾强督方治疗6个月后

除枕墙距、颌柄距无明显改变外

其余指标均有显著改善。259例患者均未出现血常规、尿常规改变及肝肾功能损害。结论补肾强督方对AS有较好疗效

且安全可靠。

Abstract

Objective:To explore clinical therapeutic effect and safety of Bushen Qiangdu Recipe on ankylosing spondylitis（AS）.Methods:259 out-patients and in-patients enrolled were treated with Bushen Qiangdu Recipe for 6 months

one dose each day for oral administration in morning and night.BAS-G

BASDAI

BASFI

Likert’ 4-grade score of spinal pain

Likert’ 4-grade score of whole body pain

duration of morning stiffness

evaluation of doctor

the occiput-wall distance

the finger-floor distance

the mandible-stermum distance

chest expansion

Schober’ test

the range of spinal movement

Gaenslen’s sign

ESR

CRP

blood and urine routine examination

renal and hepatic functions were detected before and after treatment.Results:Significant improvement was observed in all indexes except for the occiput-wall distance and the mandible-stermum distance

and no adverse effect in blood and urine routine examination and renal and hepatic function was found.Conclusion:Bushen Qiangdu Recipe has therapeutic effect on ankylosing spondylitis.

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