Clinical Study on Erzhi Tiangui Granules Combined with In Vitro Fertilization-Embryo Transplant for Treatment of 61 Cases of Infertility

Lian Fang1; Teng Yili2; Zhang Jianwei1; et al.

doi:10.13288/j.11-2166/r.2006.06.028

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Clinical Study on Erzhi Tiangui Granules Combined with In Vitro Fertilization-Embryo Transplant for Treatment of 61 Cases of Infertility

更新时间：2021-11-17

- Clinical Study on Erzhi Tiangui Granules Combined with In Vitro Fertilization-Embryo Transplant for Treatment of 61 Cases of Infertility
- Journal of Traditional Chinese Medicine Issue 6, Pages: 439-441(2006)
- 作者机构：
  
  1. 山东中医药大学附属医院
  2. 山东中医药大学
- 作者简介：
- 基金信息：
- DOI：10.13288/j.11-2166/r.2006.06.028
  CLC： R711.6
- Published：2006
- 稿件说明：
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[1]连方,滕依丽,张建伟,孙振高,刘延荷,穆琳,王琳,张宁,孟茜.二至天癸颗粒联合体外受精-胚胎移植治疗不孕症61例临床研究[J].中医杂志,2006(06):439-441.

Lian Fang1, Teng Yili2, Zhang Jianwei1, et al. Clinical Study on Erzhi Tiangui Granules Combined with In Vitro Fertilization-Embryo Transplant for Treatment of 61 Cases of Infertility[J]. Journal of Traditional Chinese Medicine2006, (6): 439-441.
[1]连方,滕依丽,张建伟,孙振高,刘延荷,穆琳,王琳,张宁,孟茜.二至天癸颗粒联合体外受精-胚胎移植治疗不孕症61例临床研究[J].中医杂志,2006(06):439-441. DOI： 10.13288/j.11-2166/r.2006.06.028.

Lian Fang1, Teng Yili2, Zhang Jianwei1, et al. Clinical Study on Erzhi Tiangui Granules Combined with In Vitro Fertilization-Embryo Transplant for Treatment of 61 Cases of Infertility[J]. Journal of Traditional Chinese Medicine2006, (6): 439-441. DOI： 10.13288/j.11-2166/r.2006.06.028.

摘要

目的观察二至天癸颗粒对不孕症患者肾气阴两虚证候的疗效

评定其对卵细胞质量

优质卵、受精卵、优质胚数目及妊娠率的影响。方法治疗组为超促排卵方案加服二至天癸颗粒

对照组单用超排。观察两组治疗前后肾气阴两虚证候改变、取卵数、优质卵率、受精率、优质胚胎率、妊娠率

统计促性腺激素（Gn）用药情况

并做相关性分析。结果肾气阴两虚证候改善、优质卵率、受精率、优质胚胎率等方面两组比较差异有显著性;治疗组Gn剂量明显少于对照组;肾气阴两虚证候改善程度与优质卵率呈正相关。结论二至天癸颗粒可明显改善肾气阴两虚证候

在不减少卵细胞数目的情况下

增加优质卵、优质胚数目

提高临床妊娠率。

Abstract

Objective:To observe effects of Erzhi Tiangui Granules on the patient of infertility with both kidney Qi and Yin deficiency

and to evaluate its effect on quality of oocytes

the number of high-quality ovum

fertilized ovum and high-quality embryo

and the clinical pregnancy rate.Methods:Patients of the treatment group were treated with promoting ovulation program and oral administration of Erzhi Tiangui Granules

and the control group with simple the promoting ovulation program.Changes of symptoms of both kidney Qi and Yin deficiency

the number of mature oocytes

the high-quality ova

fertilization rate

high-quality embryos rate

pregnancy rate and dose of gonadotropin（Gn） before and after treatment were observed

and the correlative analysis was conducted.Results:The treatment group was significantly superior to the control group in improvement of the symptoms of both kidney Qi and Yin deficiency

high-quality oocytes rate

fertility rate

high-quality embryos rate and clinical pregnancy rate

and Gn dose in the treatment group was significantly lower than that in the control group.Improvement of symptoms of both kidney Qi and Yin deficiency was positively correlated with high-quality oocytes rate.Conclusion:Erzhi Tiangui Granules can significantly improve symptoms of both kidney Qi and Yin deficiency

increase high-quality oocytes

high-quality embryo and the clinical pregnancy rate.

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Related Author

Xu Xiaofeng1

Pu Yongwen2

Related Institution

TCM Hospital of Suzhou City

Outpatient Department of China Academy of Chinese Medical Sciences

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