Clinical Observation on Qinghuang Powder for Treatment of 31 Cases of Myelodysplastic Syndrome

Xu Shu; Liu Feng; Ma Rou

doi:10.13288/j.11-2166/r.2006.07.022

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Clinical Observation on Qinghuang Powder for Treatment of 31 Cases of Myelodysplastic Syndrome

更新时间：2021-11-17

- Clinical Observation on Qinghuang Powder for Treatment of 31 Cases of Myelodysplastic Syndrome
- Journal of Traditional Chinese Medicine Issue 7, Pages: 514-515(2006)
- 作者机构：
  
  1. 中国中医研究院西苑医院血液科
  2. 中国中医研究院西苑医院血液科北京市海淀区西苑操场1号,100091
- 作者简介：
- 基金信息：
- DOI：10.13288/j.11-2166/r.2006.07.022
  CLC： R259
- Published：2006
- 稿件说明：
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[1]徐述,刘锋,麻柔.青黄散治疗骨髓增生异常综合征31例临床观察[J].中医杂志,2006(07):514-515+527.

Xu Shu, Liu Feng, Ma Rou. Clinical Observation on Qinghuang Powder for Treatment of 31 Cases of Myelodysplastic Syndrome[J]. Journal of Traditional Chinese Medicine2006, (7): 514-515.
[1]徐述,刘锋,麻柔.青黄散治疗骨髓增生异常综合征31例临床观察[J].中医杂志,2006(07):514-515+527. DOI： 10.13288/j.11-2166/r.2006.07.022.

Xu Shu, Liu Feng, Ma Rou. Clinical Observation on Qinghuang Powder for Treatment of 31 Cases of Myelodysplastic Syndrome[J]. Journal of Traditional Chinese Medicine2006, (7): 514-515. DOI： 10.13288/j.11-2166/r.2006.07.022.

摘要

目的:系统观察中药青黄散治疗骨髓增生异常综合征（MDS）的临床疗效。方法:采用随机对照方法。61例MDS患者随机分为治疗组（青黄散组）31例和对照组（维甲酸组）30例。3个月为1个疗程。结果:青黄散组总缓解率与总有效率分别为9.7%和74.1%

维甲酸组总缓解率与总有效率分别为0与46.7%

青黄散组疗效优于维甲酸组。青黄散毒副作用主要为皮肤色素沉着、角化过度及消化道症状。结论:中药青黄散治疗MDS有确切的临床疗效

能够明显改善红系造血

提高血红蛋白含量

提高白细胞数量

明显提高患者的生活质量

且患者耐受性好

对西药无效的患者仍然有效。

Abstract

Objective:To observe clinical therapeutic effect of Qinghuang Powder on myelodysplastic syndrome（MDS）.Methods:61 cases of MDS were randomly divided into a treatment group of 31 cases and a control group of 30 cases.The treatment group were treated with Qinghuang Powder and the control group with vitamin A acid.They were treated for 3 months.Results:The total remission rate was 9.7% and 0 in treatment group and control group respectively;and the total effective rat was 74.1% and 46.7% in treatment and control group

respectively.The efficacy of the treatment group was better than the control group.Main toxic-side effects in the treatment group were cutaneous pigmentation

hyperkeratosis and symptoms of the digestive tract.Conclusion:Qinghuang Powder has a definite therapeutic effect on MDS

and it can significantly improve hemopoietic function

increase hemoglobin content and count of white blood cells

and significantly improve quality of life of the patient.

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