Therapeutic Effect of Fuzheng Huayu Recipe on Bleomycin-induced Pulmonary Interstitial Fibrosis in Rats

Lu Xiong; Ye Weicheng; Liu Ping; et al.

doi:10.13288/j.11-2166/r.2006.07.035

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Therapeutic Effect of Fuzheng Huayu Recipe on Bleomycin-induced Pulmonary Interstitial Fibrosis in Rats

更新时间：2021-11-17

- Therapeutic Effect of Fuzheng Huayu Recipe on Bleomycin-induced Pulmonary Interstitial Fibrosis in Rats
- Journal of Traditional Chinese Medicine Issue 7, Pages: 538-540(2006)
- 作者机构：
  
  1. 上海中医药大学
  2. 上海中医药大学上海市浦东新区蔡伦路1200号,201203
- 作者简介：
- 基金信息：
- DOI：10.13288/j.11-2166/r.2006.07.035
  CLC： R285
- Published：2006
- 稿件说明：
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[1]陆雄,叶伟成,刘平,蔡贞贞,刘成海,张炜,谭善忠,王宝妹,林敏.扶正化瘀方对博莱霉素诱发大鼠肺间质纤维化的干预作用[J].中医杂志,2006(07):538-540.

Lu Xiong, Ye Weicheng, Liu Ping, et al. Therapeutic Effect of Fuzheng Huayu Recipe on Bleomycin-induced Pulmonary Interstitial Fibrosis in Rats[J]. Journal of Traditional Chinese Medicine2006, (7): 538-540.
[1]陆雄,叶伟成,刘平,蔡贞贞,刘成海,张炜,谭善忠,王宝妹,林敏.扶正化瘀方对博莱霉素诱发大鼠肺间质纤维化的干预作用[J].中医杂志,2006(07):538-540. DOI： 10.13288/j.11-2166/r.2006.07.035.

Lu Xiong, Ye Weicheng, Liu Ping, et al. Therapeutic Effect of Fuzheng Huayu Recipe on Bleomycin-induced Pulmonary Interstitial Fibrosis in Rats[J]. Journal of Traditional Chinese Medicine2006, (7): 538-540. DOI： 10.13288/j.11-2166/r.2006.07.035.

摘要

目的:探讨扶正化瘀方对肺纤维化的干预作用。方法:采用博莱霉素诱导肺间质纤维化模型

分别观察各组大鼠的死亡率、肺系数、肺组织羟脯氨酸（Hyp）含量以及肺组织形态学变化。结果:与模型对照组比较

扶正化瘀方能显著降低大鼠肺系数和肺组织Hyp含量

改善肺组织纤维化程度。结论:扶正化瘀方具有明显的抗博莱霉素所致的大鼠肺纤维化的作用。

Abstract

Objective:To observe therapeutic effect of Fuzheng Huayu Recipe on pulmonary fibrosis.Methods:Pulmonary fibrosis model rat was induced with bleomycin.Changes of the death rate

lung coefficient

hydroxyproline content（Hyp） in the lung tissue and morphology of the lung were investigated.Results:Compared with the model group

Fuzheng Huayu Recipe could significantly decrease the lung coefficient and Hyp content in the lung tissue and improve fibrosis of the lung tissue.Conclusion:Fuzheng Huayu Recipe has significant effect on pulmonary fibrosis induced by bleomycin in rats.

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