Effects of Paraventricular Nucleus of Hypothalamus on the Anti-Myocardial Ischemia Action of Electroacupuncture at Neiguan（PC 6）

Tu Qian1; Wang Hua2; Wang Yawen2; et al.

doi:10.13288/j.11-2166/r.2006.09.020

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Effects of Paraventricular Nucleus of Hypothalamus on the Anti-Myocardial Ischemia Action of Electroacupuncture at Neiguan（PC 6）

更新时间：2021-11-17

- Effects of Paraventricular Nucleus of Hypothalamus on the Anti-Myocardial Ischemia Action of Electroacupuncture at Neiguan（PC 6）
- Journal of Traditional Chinese Medicine Issue 9, Pages: 665-667(2006)
- 作者机构：
  
  1. 江汉大学医学与生命科学学院
  2. 湖北中医学院
- 作者简介：
- 基金信息：
- DOI：10.13288/j.11-2166/r.2006.09.020
  CLC： R245
- Published：2006
- 稿件说明：
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[1]涂乾,王华,王亚文,吴绪平.下丘脑室旁核对电针内关穴抗急性心肌缺血损伤作用的影响[J].中医杂志,2006(09):665-667.

Tu Qian1, Wang Hua2, Wang Yawen2, et al. Effects of Paraventricular Nucleus of Hypothalamus on the Anti-Myocardial Ischemia Action of Electroacupuncture at Neiguan（PC 6）[J]. Journal of Traditional Chinese Medicine2006, (9): 665-667.
[1]涂乾,王华,王亚文,吴绪平.下丘脑室旁核对电针内关穴抗急性心肌缺血损伤作用的影响[J].中医杂志,2006(09):665-667. DOI： 10.13288/j.11-2166/r.2006.09.020.

Tu Qian1, Wang Hua2, Wang Yawen2, et al. Effects of Paraventricular Nucleus of Hypothalamus on the Anti-Myocardial Ischemia Action of Electroacupuncture at Neiguan（PC 6）[J]. Journal of Traditional Chinese Medicine2006, (9): 665-667. DOI： 10.13288/j.11-2166/r.2006.09.020.

摘要

目的:探讨下丘脑室旁核在内关-心脏相关中的作用。方法:观察电针内关穴对急性缺血家兔心电图、缺血心肌细胞单相动作电位的影响及室旁核电解损毁预处理对电针内关穴效应的影响。结果:（1）电针内关穴能显著降低急性心肌缺血家兔心电图ST段电位

抑制其单相动作电位振幅衰减及时程缩短

改善心肌超微结构;（2）下丘脑室旁核电解损毁能显著降低电针内关穴效应。结论:（1）电针内关穴能抗家兔急性心肌缺血损伤;（2）下丘脑室旁核参与内关—心脏相关的中枢通路。

Abstract

Objective:To study the role of paraventricular nucleus of hypothalamus（PVN） in correlativity between Neiguan（PC 6） and the heart.Methods:Effects of electroacupuncture （EA） at Neiguan（PC 6） on ECG and monophasic action potential （MAP） of ischemic myocardial cells

and changes of these effects after electrolytic lesion of PVN were investigated in the rabbit of acute myocardial ischemia.Results:（1） EA at Neiguan（PC 6） could significantly reduce ST potential of ECG

inhibit the decline of MAPA and shortening of MAPD

and improve the myocardial ultrastructure in the rabbit of acute myocardial ischemia; （2）Electrolytic lesion of PVN could significantly decrease the effects of EA at Neiguan（PC 6）.[WTHZ]Conclusion:EA at Neiguan（PC 6） can significantly attenuate the injury of acute myocardial ischemia

and PVN participates in the central pathway of Neiguan（PC 6） to the heart.

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