Hu Rui, Deng Hong, Tang Fang. Effect of Renshen Yangrong Decoction on Cerebral Neuron Form and Density in Aging Mice[J]. Journal of Traditional Chinese Medicine2006, (11): 859-860.
Hu Rui, Deng Hong, Tang Fang. Effect of Renshen Yangrong Decoction on Cerebral Neuron Form and Density in Aging Mice[J]. Journal of Traditional Chinese Medicine2006, (11): 859-860.DOI: 10.13288/j.11-2166/r.2006.11.033.
Effect of Renshen Yangrong Decoction on Cerebral Neuron Form and Density in Aging Mice
Objective:To observe effects of Renshen Yangrong Decoction on appearance
body weight increasing rate
death rate and cerebral neuron form and density in the sub-acute mice.Methods:Sixty-nine ICR mice were randomly divided into a control group
and a model group
a Chinese medicine group
23 mice in each group.Mice in model group and Chinese medicine group were given D-galactose to make aging model
and the control group were subcutaneously injected with saline.Chinese medicine group were treated with Renshen Yangrong Decoction.Changes of cerebral tissue form and density were observed after Golgi stain under light microscope.Results:Renshen Yangrong Decoction could significantly inhibit the decrease of neuron density of the cerebral cortex (P<0.01) and did not significantly influence the neuron density of the hippocampus.Conclusion:The protective action of Renshen Yangrong Decoction on neurons of the cerebral cortex is possibly one of mechanisms of its anti-aging effect.