Clinical Study on Puerarin Injection Combined with Vitamin C for Treatment of 52 Cases of Type II Diabetic Nephropathy

Li Qiangxiang~1; He Meiying~2; Zhong Huiju~3; et al.

doi:10.13288/j.11-2166/r.2006.12.020

您当前的位置：

首页 >

文章列表页 >

Clinical Study on Puerarin Injection Combined with Vitamin C for Treatment of 52 Cases of Type II Diabetic Nephropathy

更新时间：2021-11-17

- Clinical Study on Puerarin Injection Combined with Vitamin C for Treatment of 52 Cases of Type II Diabetic Nephropathy
- Journal of Traditional Chinese Medicine Issue 12, Pages: 912-914(2006)
- 作者机构：
  
  1. 湖南省娄底市中心医院
  2. 湖南省常宁市中医院
  3. 中南大学湘雅医院
- 作者简介：
- 基金信息：
- DOI：10.13288/j.11-2166/r.2006.12.020
  CLC： R587.2
- Published：2006
- 稿件说明：
移动端阅览
[1]李强翔,何美英,钟慧菊,龚汉仁,申道君,李小白.葛根素注射液与维生素C联用治疗2型糖尿病肾病52例临床研究[J].中医杂志,2006(12):912-914.

Li Qiangxiang~1, He Meiying~2, Zhong Huiju~3, et al. Clinical Study on Puerarin Injection Combined with Vitamin C for Treatment of 52 Cases of Type II Diabetic Nephropathy[J]. Journal of Traditional Chinese Medicine2006, (12): 912-914.
[1]李强翔,何美英,钟慧菊,龚汉仁,申道君,李小白.葛根素注射液与维生素C联用治疗2型糖尿病肾病52例临床研究[J].中医杂志,2006(12):912-914. DOI： 10.13288/j.11-2166/r.2006.12.020.

Li Qiangxiang~1, He Meiying~2, Zhong Huiju~3, et al. Clinical Study on Puerarin Injection Combined with Vitamin C for Treatment of 52 Cases of Type II Diabetic Nephropathy[J]. Journal of Traditional Chinese Medicine2006, (12): 912-914. DOI： 10.13288/j.11-2166/r.2006.12.020.

摘要

目的:观察葛根素注射液联用维生素C对2型糖尿病肾病的治疗作用及机制。方法:将确诊为2型糖尿病肾病的145例患者随机分为3组。治疗组52例

在常规治疗基础上给予葛根素注射液静脉滴注

并口服维生素C;对照A组48例

在常规治疗基础上加用葛根素静脉滴注;对照B组45例

在常规治疗基础上加服维生素C

3组均以2周为1个疗程。观察3组治疗前后尿素氮、血肌酐、血脂、糖化血红蛋白、丙二醛、超氧化物歧化酶、24小时尿白蛋白排泄率等指标的变化。结果:治疗组治疗后除尿素氮、血肌酐、糖化血红蛋白外其他各项指标与治疗前相比均有显著改善（P<0.01）。结论:葛根素注射液、维生素C均有较好的改善肾功能及降低尿蛋白排泄率的作用。二者合用有协同作用

治疗2型糖尿病肾病的疗效比单用葛根素或维生素C好。

Abstract

Objective:To observe the therapeutic effect and mechanisms of Puerarin injection combined with vitamin C for treatment of type II diabetic nephropathy.Methods:On the basis of routine treatment

145 cases of type II diabetic nephropathy were randomly divided into a treatment group（n=52） treated with intravenous drip of Puerarin injection and vitamin C

a control group A（n=48） treated with intravenous drip of simple Puerarin injection

and a control group B（n=45） treated with simple vitamin C.Two weeks constituted one course.Changes of urea nitrogen

serum creatinine

blood lipid

glycosylated hemoglobin

MDA

SOD and 24-hour urine albumin excretion rate before and after treatment were investigated. Results: After treatment

investigated indexes except urea nitrogen

serum creatinine and glycosylated hemoglobin

improved significantly in the treatment group （P<0.01）.Conclusion:Puerarin injection and vitamin C can markedly improve renal function and decrease urinary protein excretion rate with synergistic action.The effect of combined use on type Ⅱ diabetic nephropathy is superior to that of simple Puerarin injection or vitamin C.

关键词

Keywords

references

查看原文

Views

186

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

Clinical Efficacy and Economic Evaluation of 1293 Non-Severe Adult Patients with Community-Acquired Pneumonia Treated by the Jiangsu Traditional Chinese Medicine Diagnosis and Treatment Protocol for Dominant Diseases：A Multicenter，Retrospective Real-World Cohort Study

A Preliminary Discussion on the Method of Regulating Qi and Calming the Mind

Efficacy and Economic Evaluation of Weishi Qingjin Formula （苇石清金方）in the Treatment of Adult Community-Acquired Pneumonia with Phlegm-Heat Obstructing the Lung Syndrome：A Multicenter Retrospective Real-World Cohort Study

Construction and Application of a Real-World Cohort of Community-Acquired Pneumonia Based on a Multimodal Large-Scale Traditional Chinese Medicine Big Data Platform

Syndrome Differentiation and Treatment of Cholinergic Urticaria from the Perspective of "Treating Fire Constraint by Dispersing It"

Related Author

No data

Related Institution

No data

Address：No.16, Nanxiao street, Dongzhimen, Dongcheng District, Beijing Postal code：100700
Tel：010-64035632 Email：jtcmcn@188.com
Technical support is provided by Beijing Founder electronics co., LTD 京ICP备09064830号-19 京公网安备11010102007558号
It is recommended to read the content of this site in Chrome&IE9+. Please switch to extreme mode in browser 360.
Cookies We use cookies to help provide and enhance our service and tailor content. By continuing, you agree to the use of cookies.

⁰