WANG Chun1, CHENG Zhi-qing2. Pinggan Yishen Ditan Decoction for Hypertensive Obesity:A Clinical Observation of 31 Cases[J]. Journal of Traditional Chinese Medicine2007, (2): 135-137.
WANG Chun1, CHENG Zhi-qing2. Pinggan Yishen Ditan Decoction for Hypertensive Obesity:A Clinical Observation of 31 Cases[J]. Journal of Traditional Chinese Medicine2007, (2): 135-137.DOI: 10.13288/j.11-2166/r.2007.02.017.
Pinggan Yishen Ditan Decoction for Hypertensive Obesity:A Clinical Observation of 31 Cases
Objective To observe the therapeutic effect of Pinggan Yishen Ditan Decoction (Liver-Calming Kidney-Boosting Phlegm-Flushing Decoction) for hypertensive obesity and its possible mechanism.Methods Sixty cases of hypertensive obesity were randomly divided into Chinese medicine group (Chinese medicine was added on the basis of treatment in control group) and control group.The treatment course lasted for 8 weeks.Blood pressure (BP)
body weight
waist circum-ference(WC)
waist-to-hip ratio(WHR)
metabolism parameters
fasting insulin(FINS) and Leptin were observed and compared before and after treatment.Results There was significant difference in SBP
DBP
BMI
WC
WHR
FPG
TC
TG
HDL-C
LDL-C
FINS
Leptin and ISI after treatment in Chinese medicine group (P<0.05 or P<0.01)
and there was significant difference in SBP
DBP FPG TC
HDL-C
LDL-C and ISI between the two groups (P<0.05).Conclusion Chinese medicine treatment can improve BP
body weight and BMI and regulate metabolism parameters for hypertensive obesity on the basis of moderate exercises
rational diet and enalapril meleate
which maybe relvant to its increasing insulin sensitivity and decreasing Leptin.
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