Effect of Qi-Boosting Phlegm-Transforming and Goiter-Dispersing on Serum Thyroglobulin Antibody and Thyroperoxydase Antibody in Hashimoto’s Thyroiditis Patients

ZHANG Min; ZHANG Yi

doi:10.13288/j.11-2166/r.2007.05.013

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Effect of Qi-Boosting Phlegm-Transforming and Goiter-Dispersing on Serum Thyroglobulin Antibody and Thyroperoxydase Antibody in Hashimoto’s Thyroiditis Patients

更新时间：2021-11-17

- Effect of Qi-Boosting Phlegm-Transforming and Goiter-Dispersing on Serum Thyroglobulin Antibody and Thyroperoxydase Antibody in Hashimoto’s Thyroiditis Patients
- Journal of Traditional Chinese Medicine Issue 5, Pages: 414-415(2007)
- 作者机构：
  
  1. 上海市中医医院内分泌科
  2. 上海市中医医院内分泌科上海市芷江中路274号,200071
- 作者简介：
- 基金信息：
- DOI：10.13288/j.11-2166/r.2007.05.013
  CLC： R26
- Published：2007
- 稿件说明：
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[1]张敏,张毅.益气化痰消瘿法对桥本甲状腺炎患者血清甲状腺球蛋白抗体、甲状腺过氧化物酶抗体的影响[J].中医杂志,2007(05):414-415.

ZHANG Min, ZHANG Yi. Effect of Qi-Boosting Phlegm-Transforming and Goiter-Dispersing on Serum Thyroglobulin Antibody and Thyroperoxydase Antibody in Hashimoto’s Thyroiditis Patients[J]. Journal of Traditional Chinese Medicine2007, (5): 414-415.
[1]张敏,张毅.益气化痰消瘿法对桥本甲状腺炎患者血清甲状腺球蛋白抗体、甲状腺过氧化物酶抗体的影响[J].中医杂志,2007(05):414-415. DOI： 10.13288/j.11-2166/r.2007.05.013.

ZHANG Min, ZHANG Yi. Effect of Qi-Boosting Phlegm-Transforming and Goiter-Dispersing on Serum Thyroglobulin Antibody and Thyroperoxydase Antibody in Hashimoto’s Thyroiditis Patients[J]. Journal of Traditional Chinese Medicine2007, (5): 414-415. DOI： 10.13288/j.11-2166/r.2007.05.013.

摘要

目的观察益气化痰消瘿法中药对桥本甲状腺炎血清中甲状腺球蛋白抗体（TGAb）、甲状腺过氧化物酶抗体（TPOAb）的影响。方法将60例桥本甲状腺炎患者随机分为治疗组30例和对照组30例。两组患者甲状腺功能均经西药控制在正常范围;治疗组在此基础上加用益气化痰消瘿中药治疗。结果在降低TGAb、TPOAb值方面

治疗组治疗前后自身比较及治疗组与对照组治疗后相互比较差异均有显著性意义（P<0.05或P<0.01）。在改善甲状腺肿大方面

治疗组疗效也具有显著性意义（P<0.05）。结论中药治疗能有效降低甲状腺自身免疫性抗体指标

并且对甲状腺肿大有效。

Abstract

Objective To observe the effect of qi-boosting phlegm-transforming and goiter-dispersing medicinals on thyroglobulin antibody （TGAb） and thyroperoxydase antibody （TPOAb） in Hashimoto’s thyroiditis （HT） patients. Methods Totally 60 cases of HT were randomly and equally divided into treatment group and control group. Western medical treatment was conducted in control group

while qi-boosting phlegm-transforming and goiter-dispersing medicinals were added in treatment group. Results After treatment

TGAb and TPOAb decreased significantly in treatment group with significant differences between two groups（P<0.05 or P<0.01）. Thyromegaly was significantly relieved in treatment group as well（P<0.05）. Conclusion Chinese medicinals can down regulate the indexes of thyreoid autoimmune antibodies and have therapeutic effect on thyromegaly.

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