Objective To study the therapeutic effect of Supplemented Siwu Decoction for type 2 diabetes with asymptomatic hyperuricemia. Methods Totally 76 patients according to the diagnostic code of diabetes and asymptomatic hyperuricemia were randomly and equally divided into two groups.Cozaar and Supplemented Siwu Decoction were given once a day to control and treatment groups respectively for 3 months.Fasting plasma glucose

insulin

blood pressure

cholesterol

triglyeride

body mass index

serum uric acid（SUA）

serum creatinine

urine uric acid（UUA）

urine creatinine

urine pH value and urine microamount albumin（U-mAlb） were observed before and after treatment.Clearance of uric acid

clearance of creatinine and fraction of uric acid clearance were calculated as well. Results The total effective rates of treatment and control groups were 81.58% and 60.53% respectively

resulting in significant difference （P<0.01）.Treatment group had better effect on SUA

urine pH value

UUA and 24-hour urine volume than control group（P<0.01 or P<0.05）.Control group had better effect on U-mAlb and diastolic blood pressure than treatment group（P<0.05）. Conclusion Supplemented Siwu Decoction has obvious effect for diabetes with asymptomatic hyperuricemia.