Objective To study the effect of Ailuo Kechuanning Oral Liquid on interleukin-2 （IL-2） and interleukin-13 （IL-13） in bronchial asthma （BA） patients.Methods BA patients with phlegm-damp obstructing the lung pattern were randomly divided into treatment and control groups. Ailuo Kechuanning Oral Liquid was used in treatment group and Xiaokechuan Syrup in control group. The therapeutic effect and change of IL-2 and IL-13 of both groups were observed before and after treatment.Results The recovery and total effective rates of treatment group were superior to those of control group （P<0.05）. The level of IL-2 in treatment group decreased significantly as compared with control group （P<0.05）. There was no significant difference in IL-13 between two groups （P>0.05）.Conclusion Ailuo Kechuanning Oral Liquid is effective for BA and the effect may be relevant to decreasing the level of IL-2 and inhibiting T lymphocyte immunity.