Effect of Yishen Lishui Recipes on Vascular Permeability of the Patients with Ovarian Hyper-Stimulation Syndrome

LIU Feng-yun1; WU Xian-zhe2; ZHANG Min3; et al.

doi:10.13288/j.11-2166/r.2007.11.039

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Effect of Yishen Lishui Recipes on Vascular Permeability of the Patients with Ovarian Hyper-Stimulation Syndrome

更新时间：2021-11-17

- Effect of Yishen Lishui Recipes on Vascular Permeability of the Patients with Ovarian Hyper-Stimulation Syndrome
- Journal of Traditional Chinese Medicine Issue 11, Pages: 989-991(2007)
- 作者机构：
  
  1. 深圳市第五人民医院妇产科、中心实验室、生殖医学中心
  2. 深圳市第五人民医院妇产科、中心实验室、生殖医学中心广东省深圳市友谊路47号
  3. ,518001
- 作者简介：
- 基金信息：
- DOI：10.13288/j.11-2166/r.2007.11.039
  CLC： R271.9
- Published：2007
- 稿件说明：
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[1]刘凤云,吴先哲,张敏,郭广洲,黄志欣.益肾利水方对卵巢过度刺激综合征患者血管通透性的影响[J].中医杂志,2007(11):989-991.

LIU Feng-yun1, WU Xian-zhe2, ZHANG Min3, et al. Effect of Yishen Lishui Recipes on Vascular Permeability of the Patients with Ovarian Hyper-Stimulation Syndrome[J]. Journal of Traditional Chinese Medicine2007, (11): 989-991.
[1]刘凤云,吴先哲,张敏,郭广洲,黄志欣.益肾利水方对卵巢过度刺激综合征患者血管通透性的影响[J].中医杂志,2007(11):989-991. DOI： 10.13288/j.11-2166/r.2007.11.039.

LIU Feng-yun1, WU Xian-zhe2, ZHANG Min3, et al. Effect of Yishen Lishui Recipes on Vascular Permeability of the Patients with Ovarian Hyper-Stimulation Syndrome[J]. Journal of Traditional Chinese Medicine2007, (11): 989-991. DOI： 10.13288/j.11-2166/r.2007.11.039.

摘要

目的比较中西医结合方法与西药常规治疗卵巢过度刺激综合征（OHSS）的临床疗效

探讨益肾利水方的治疗作用机制。方法将30例OHSS患者随机分为中西医结合治疗组（治疗组）与西药对照组（西药对照组）各15例。同步观察两组临床疗效

比较两组患者血清中血管内皮生长因子（VEFG）、白细胞介素6（IL-6）的含量。结果治疗组在痊愈率、使用白蛋白及放腹水病例数等方面明显优于对照组（P<0.05）。治疗组患者血清VEGF水平基本降至正常范围

而西药对照组血清VEGF水平仍显著高于正常组。结论益肾利水方能增强OHSS患者的临床疗效

减少白蛋白使用

其作用可能是通过降低患者血管通透性而实现的。

Abstract

Objective To compare the clinical effect of integrated Chinese and western medicine and the routine treatment of western medicine on ovarian hyper-stimulation syndrome （OHSS） to discuss the mechanism of Yishen Lishui （tonify kidney and induce diuresis） Recipes for it.Methods The 30 OHSS patients were randomized into the treated group （treated by integrated Chinese and western medicine） and the control group （treated by western medicine） with 15 in each. Compare the effect of different treatments on vascular endothelial growth factor （VEGF） and interleukin-6 （IL-6） of two groups.Results In the treated group

the curative rate

number of patients using albumin and large volume paracentesis （LVP） were significantly superior to those of the control group （P<0.05）. The VEGF of the treated group decreased to normal range and VEGF of the control group was obviously higher than that of the normal group.Conclusion Yishen Lishui Recipes can raise the therapeutic effect for OHSS patients and reduce consumption of albumin. The function may be realized through reducing the vascular permeability.

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