Clinical Observation on 30 Cases of Acute Osteoarthritis of Knee Joint Treated by Sishen Jian

PAN Zheng Zhou Cai-yun

doi:10.13288/j.11-2166/r.2007.12.013

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Clinical Observation on 30 Cases of Acute Osteoarthritis of Knee Joint Treated by Sishen Jian

更新时间：2021-11-17

- Clinical Observation on 30 Cases of Acute Osteoarthritis of Knee Joint Treated by Sishen Jian
- Journal of Traditional Chinese Medicine Issue 12, Pages: 1087-1088(2007)
- 作者机构：
  
  1. 中国中医科学院西苑医院风湿免疫科
  2. 中国中医科学院西苑医院风湿免疫科北京市海淀区西苑操场1号
  3. ,100091
- 作者简介：
- 基金信息：
- DOI：10.13288/j.11-2166/r.2007.12.013
  CLC： R274
- Published：2007
- 稿件说明：
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[1]潘峥,周彩云.四神煎治疗膝骨关节炎急性期30例临床观察[J].中医杂志,2007(12):1087-1088.

PAN Zheng Zhou Cai-yun. Clinical Observation on 30 Cases of Acute Osteoarthritis of Knee Joint Treated by Sishen Jian[J]. Journal of Traditional Chinese Medicine2007, (12): 1087-1088.
[1]潘峥,周彩云.四神煎治疗膝骨关节炎急性期30例临床观察[J].中医杂志,2007(12):1087-1088. DOI： 10.13288/j.11-2166/r.2007.12.013.

PAN Zheng Zhou Cai-yun. Clinical Observation on 30 Cases of Acute Osteoarthritis of Knee Joint Treated by Sishen Jian[J]. Journal of Traditional Chinese Medicine2007, (12): 1087-1088. DOI： 10.13288/j.11-2166/r.2007.12.013.

摘要

目的观察四神煎治疗膝骨关节炎急性期的临床疗效。方法将60例膝骨关节炎急性期患者随机分为治疗组与对照组

每组各30例。治疗组予以四神煎合用英太青（双氯芬酸钠缓释胶囊）治疗

对照组单以英太青口服

疗程2周。治疗前后观察晨僵、关节肿胀、关节发热、关节压痛4项症状、体征和血沉、C-反应蛋白。结果治疗组的总有效率为96.66%

对照组的总有效率为73.33%

两组比较差异具有显著性意义（P<0.05）;治疗组在改善患者晨僵、关节肿胀、关节发热、关节压痛和降低C-反应蛋白方面均优于对照组。结论四神煎治疗膝骨关节炎急性期疗效明显

是临床有效方剂。

Abstract

Objective To observe the clinical effect of herbal decoction Sishen Jian on acute osteoarthritis of knee joint.Methods The 60 osteoarthritis cases in the attack stage were randomized into treatment group（30 cases）and control group（30 cases）.The treatment group was given the decoction Sishen Jian and Diclofenac Sodium Sustained Release Capsules and the control group was given the capsules only.Two weeks made one course of treatment.Before and after treatment

the symptoms such as pain and morning stiff- ness

the signs including joint swelling and tenderness

and the erythrocyte sedimentation rate（ESR）and C reactive protein were ob- served for comparison.Results The total effective rate of the treatment group and control group was 96.66% and 53.26% respec- tively.The difference of two groups was significant（P<0.05）.In terms of relieving pain

morning stiffness

joint swelling and ten- derness

and decreasing the level of CRP

the effect of treatment group was superior to that of the control group.Conclusion The herbal decoction Sishen Jian is effective for acute osteoarthritis of knee joint.

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