Objective To explore the major related influencing factors of Yang-deficiency constitution in Chinese medicine.Meth- ods The 2

230 healthy people and patients above the age of 15 were selected from the communities and medical examination center of the five areas

i.e.east

west

south

north and central areas of China to conduct a cross-section investigation

A written informed con- sent was obtained from each participant.The standard Constitution in Chinese Medicine Questionnaire（CCMQ）was adopted to deter- mine the scores of Yang-deficiency constitution and the single factor analysis and multiple stepwise regression analysis were employed to analyze major influencing factors.Results Seven influencing factors entered into the regression equation by multiple stepwise regres- sion analysis

they were in an order as

from-more-to-less in influencing degree

chronic disease

female

no exercise habit

preferring hot drinks and food

slim body build

on bland diet

and not breast feeding after born.Conclusion Diseases

sex

exercise habits

diet and body build are the major influential factors of the Yang-deficiency constitution in Chinese medicine.