Objective To evaluate the effect of the acupuncture method "regulating the sea of marrow

circulating yang and soothing tendon" on quality of life （QOL） and activity of daily life（ADL） in hemiplegia patients. Methods Totally 400 hemiplegia patients were randomized into the treatment group（by the method of regulating the sea of marrow） and the control group（by standard acupuncture）. Prospective

multi-centered

randomized-controlled

and single-blinded method were used. Barthel Index （BI） and WHO QOL-100 were selected to evaluate QOL and ADL. Results BI and improvement of disabled activities of both groups were significantly improved while the effect of treatment group was better. In addition

the scores of WHO QOL-100 and stroke-specific quality of life scale of both groups were also increased and the effect of treatment group was superior to that of control group. Conclusion The acupuncture method of "regulating the sea of marrow

circulating yang and soothing tendon" can significantly improve ADL and QOL of hemiplegia patients.