A Multi-Centered,Randomized-Controlled Clinical Study on Suhuang Zhike Capsule for Cough Variant Asthma

ZHANG Yan-ping1; MIAO Qing1; CHAO Yan2; et al.

doi:10.13288/j.11-2166/r.2008.06.010

您当前的位置：

首页 >

文章列表页 >

A Multi-Centered,Randomized-Controlled Clinical Study on Suhuang Zhike Capsule for Cough Variant Asthma

更新时间：2021-11-17

- A Multi-Centered,Randomized-Controlled Clinical Study on Suhuang Zhike Capsule for Cough Variant Asthma
- Journal of Traditional Chinese Medicine Issue 6, Pages: 504-506(2008)
- 作者机构：
  
  1. 中国中医科学院西苑医院呼吸科
  2. 北京东方运嘉科技发展有限公司
  3. 广州中医药大学附属医院
  4. 天津中医药大学附属第二医院
  5. 河南中医学院第一附属医院
  6. 辽宁中医药大学附属医院
  7. 华中科技大学同济医学院附属协和医院
  8. 安徽省药物临床评价中心
  9. 卫生部中日友好医院北京市海淀区西苑操场1号
  10. ,100091
- 作者简介：
- 基金信息：
- DOI：10.13288/j.11-2166/r.2008.06.010
  CLC： R256.1
- Published：2008
- 稿件说明：
移动端阅览
[1]张燕萍,苗青,晁燕,赵丹,林琳,孙增涛,李素云,徐艳玲,沈霖,黄继汉,张旭丽,晁恩祥.苏黄止咳胶囊治疗咳嗽变异性哮喘的随机对照多中心临床研究[J].中医杂志,2008(06):504-506.

ZHANG Yan-ping1, MIAO Qing1, CHAO Yan2, et al. A Multi-Centered,Randomized-Controlled Clinical Study on Suhuang Zhike Capsule for Cough Variant Asthma[J]. Journal of Traditional Chinese Medicine2008, (6): 504-506.
[1]张燕萍,苗青,晁燕,赵丹,林琳,孙增涛,李素云,徐艳玲,沈霖,黄继汉,张旭丽,晁恩祥.苏黄止咳胶囊治疗咳嗽变异性哮喘的随机对照多中心临床研究[J].中医杂志,2008(06):504-506. DOI： 10.13288/j.11-2166/r.2008.06.010.

ZHANG Yan-ping1, MIAO Qing1, CHAO Yan2, et al. A Multi-Centered,Randomized-Controlled Clinical Study on Suhuang Zhike Capsule for Cough Variant Asthma[J]. Journal of Traditional Chinese Medicine2008, (6): 504-506. DOI： 10.13288/j.11-2166/r.2008.06.010.

摘要

目的观察苏黄止咳胶囊治疗咳嗽变异性哮喘（CVA）的临床有效性及安全性。方法以止咳宁嗽胶囊为阳性对照

采用随机、双盲、多中心平行对照临床试验。选择符合研究标准的CVA患者279例

苏黄止咳胶囊组（治疗组）209例

完成196例;止咳宁嗽胶囊组（对照组）70例

完成69例。疗程2周

观察两组患者中医症状、治疗前后肺功能和激发试验情况。结果咳嗽总疗效:治疗组愈显率61.22%

总有效率90.31%;对照组分别为36.23%及72.46%

治疗组优于对照组（P<0.05）。中医证候综合疗效:治疗组愈显率62.76%

总有效率91.84%;对照组分别为27.54%及81.16%

治疗组优于对照组（P<0.05）。支气管激发试验治疗前后比较

治疗组部分患者复查激发试验转为阴性

与对照组比较差异有统计学意义（P<0.05）。结论苏黄止咳胶囊治疗CVA疗效显著

能够降低气道高反应性。

Abstract

Objective To observe the effect and safety of Suhuang Zhike Capsule on cough variant asthma（CVA）.Methods In the multi-centered randomized controlled double-blinded clinical study

279 CVA cases were divided into the treatment group treated by Suhuang Zhike Capsule（196 of 209 cases completed the treatment）

and the control group treated by Zhike Ningsou Capsule（69 of 70 cases completed the treatment）.The treatment course was 2 weeks.The improvement in TCM symptoms

lung function and bronchial challenge test were observed.Results On the total effect

in the treatment group

the total effective rate was 90.31 % and the curative rate 61.22%;in the control group

the total effective rate was 72.46 % and the curative rate 36.23%.The former was superior to the latter（P<0.05）.On the comprehensive effect of TCM symptoms

in the treatment group

the total effective rate was 91.84 % and the curative rate 62.76%;in the control group

the total effective rate was 81.16 % and the curative rate 27.54%.The former was superior to the latter（P<0.05）.After treatment

the bronchial challenge test in some cases of the treatment group changed to negative

showing a significant difference from the control group（P<0.05）.Conclusion Suhuang Zhike Capsule has an obvious therapeutic effect on CVA by reducing the bronchial reaction of patient.

关键词

Keywords

references

查看原文

Views

1171

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

百茅汤辨治儿童痉挛性咳嗽经验

中医药在肺结节全程管理中的优势及展望

和调枢机法治疗咳嗽变异性哮喘

近五年中医药治疗原发性支气管肺癌临床研究概况

Retrospective Analysis of Clinical Literature on Chinese Medicine for AIDS

Related Author

郭素香

崔慧娟

董慧静

鲁星妤

俞仪萱

胡紫馨

李嘉

薛崇祥

Related Institution

天津中医药大学第二附属医院，天津市河北区增产道69号

中日友好医院

北京中医药大学中日友好临床医学院，北京市朝阳区樱花园东街2号

北京中医药大学

北京中医药大学第三附属医院，北京市朝阳区安外小关街51号

Address：No.16, Nanxiao street, Dongzhimen, Dongcheng District, Beijing Postal code：100700
Tel：010-64035632 Email：jtcmcn@188.com
Technical support is provided by Beijing Founder electronics co., LTD 京ICP备09064830号-19 京公网安备11010102007558号
It is recommended to read the content of this site in Chrome&IE9+. Please switch to extreme mode in browser 360.
Cookies We use cookies to help provide and enhance our service and tailor content. By continuing, you agree to the use of cookies.

⁰