Clinical Study on the Effect of Ganzhixiao Capsule on Nonalcoholic Fatty Liver Disease of 22 Cases

DONG Hui; LU Fu-er; WANG Nan; et al.

doi:10.13288/j.11-2166/r.2008.06.014

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Clinical Study on the Effect of Ganzhixiao Capsule on Nonalcoholic Fatty Liver Disease of 22 Cases

更新时间：2021-11-17

- Clinical Study on the Effect of Ganzhixiao Capsule on Nonalcoholic Fatty Liver Disease of 22 Cases
- Journal of Traditional Chinese Medicine Issue 6, Pages: 514-516(2008)
- 作者机构：
  
  1. 华中科技大学同济医学院附属同济医院
  2. 华中科技大学同济医学院附属同济医院武汉市解放大道1095号
  3. ,430030
- 作者简介：
- 基金信息：
- DOI：10.13288/j.11-2166/r.2008.06.014
  CLC： R259
- Published：2008
- 稿件说明：
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[1]董慧,陆付耳,王南,饶晶晶,魏世超,徐丽君,邹欣.肝脂消胶囊治疗非酒精性脂肪肝22例临床观察[J].中医杂志,2008(06):514-516.

DONG Hui, LU Fu-er, WANG Nan, et al. Clinical Study on the Effect of Ganzhixiao Capsule on Nonalcoholic Fatty Liver Disease of 22 Cases[J]. Journal of Traditional Chinese Medicine2008, (6): 514-516.
[1]董慧,陆付耳,王南,饶晶晶,魏世超,徐丽君,邹欣.肝脂消胶囊治疗非酒精性脂肪肝22例临床观察[J].中医杂志,2008(06):514-516. DOI： 10.13288/j.11-2166/r.2008.06.014.

DONG Hui, LU Fu-er, WANG Nan, et al. Clinical Study on the Effect of Ganzhixiao Capsule on Nonalcoholic Fatty Liver Disease of 22 Cases[J]. Journal of Traditional Chinese Medicine2008, (6): 514-516. DOI： 10.13288/j.11-2166/r.2008.06.014.

摘要

目的观察肝脂消胶囊治疗非酒精性脂肪肝（NAFLD）的疗效。方法依据中华医学会NAFLD诊断标准入选NAFLD患者（NAFLD组）22例并与20名健康人（正常组）对照。两组均进行常规体检和肝脏CT扫描

以CT肝/脾比值做为疗效评价指标。NAFLD组患者服用肝脂消胶囊8周

检测治疗前后血清生化指标和CT肝/脾比值的变化。结果NAFLD组血清丙氨酸氨基转移酶（ALT）、甘油三酯（TG）较正常组明显升高

CT肝/脾比值较正常组明显降低（P<0.01）。经治疗后ALT、TG均明显下降

CT肝/脾比值升高（P<0.05或P<0.01）。结论肝脂消胶囊治疗NAFLD疗效肯定。

Abstract

Objective To investigate the effect of Ganzhixiao Capsule（Capsule for liver fat dissolving） in treating nonalcoholic fatty liver disease（NAFLD）.Methods The 22 patients were selected according to the Chinese Medical Association’s diagnostic standard of NAFLD and compared with 20 healthy persons（control group）.Both groups were given routine medical checkup and liver CT scanning and then the liver/spleen ratio was taken as the index for effect evaluation.The NAFLD patients were administered Ganzhixiao Capsule for 8 weeks

and the changes of biochemical indexes and CT liver/spleen ratio after treatment were observed for comparison.Results In NAFLD group

the serum alanine aminotransferase（ALT） and triglyceride（TG） were significantly increased while the CT liver/spleen ratio was significantly decreased in comparing with the control group.After treatment

ALT and TG decreased significantly while liver/spleen ratio increased（P<0.05 or P<0.01）.Conclusion Ganzhixiao Capsule treats NAFLD effectively.

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