Objective To observe the clinical effect of Shuguanling（Chinese medicine for dredging the oviduct） on salpingemphraxis sterility and to study its mechanism.Methods The diagnosed patients were randomized into 3 groups with 52 in each.The treatment group was administered Shuguanling p.o.and clyster.The control group A was given Xuefu Zhuyu Oral Liquid（Oral liquid for removing blood stasis in the abdomen）

and Kangfu Xiaoyan Pills（Pills for recovery of gynecological inflammation） suppository into recta.The control group B was prescribed Xuefu Zhuyu Oral Liquid and vaginal culdocentesis with the mixture of dexamethasone

chymotrypsin

gentamicin and normal saline.After three months

the effect was evaluated and the pelvic blood flow

blood viscosity

plasma collagenase

fibrinogen and fibrinolytic activity of the treatment group were tested for comparison.Results The tubal patency rate and pregnancy rate of treatment group were significantly higher than those of control groups（P<0.01）.There was a significant difference in the treatment group in the maximum blood flow of left uterus artery

the pulsating index（PI）

resisting index（RI） of left ovary artery

and RI of right ovary artery after medication compared with before treatment（P<0.05）.The significant difference was also present in plasma collagenase

fibrinogen

and fibrinolytic activity of the treatment group（P<0.05）.And the whole blood viscosity

plasma viscosity

and packed cell volume showed significant difference as well（P<0.05）.Conclusion Shuguanling can improve pelvic blood flow

reduce blood viscosity

increase fibrinolytic and collagenase activity

relieve the adhesion of inflammatory tissues

and promote inflammative absorption

serving as an ideal medicine for salpingemphraxis sterility.