Objective To observe the effect of self-made formula to promote circulation of qi and activate blood on herpes zoster of TCM syndrome of heat stagnated in liver meridian. Methods The 70 herpes zoster cases of heat stagnated in liver meridian in TCM syndrome were randomized into treatment group and control group. Two groups were administered respectively the self-made formula and Longdan Xiegan Decoction for oral taking for two weeks based on the treatment of Acyclovir Sustained Release Tablets and Erwei Badu Powder （Powder of Two herbs for removing toxins） for external application for one week. The therapeutic effect was evaluated after two weeks’treatment. Results The pain relieve in the treatment group was more obvious than that of the control group （P<0.05）. There was no significant difference in both groups in relieving symptoms （P>0.05）. One month after treatment

only one case in the treatment group but 4 in the the control group had postherpetic neuralgia. Comparing the two groups in pain relieving

the total effective rate of treatment group was 77.14%

better than that of the control group

58.06%

the therapeutic effect of the treatment group is superior to that of the control group（P<0.05）. Conclusion The self-made formula to promote circulation of qi and activate blood has definit effect on herpes zoster TCM syndrome of heat stagnated in liver meridian and no adverse effect was found.