Clinical Study on the Effect of Qufeng Zhidong Decoction on 31 Cases of Children Tic Disorder

WU Min1; XIAO Guanghua2; ZHANG Jianming1; et al.

doi:10.13288/j.11-2166/r.2009.05.047

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Clinical Study on the Effect of Qufeng Zhidong Decoction on 31 Cases of Children Tic Disorder

更新时间：2021-11-17

- Clinical Study on the Effect of Qufeng Zhidong Decoction on 31 Cases of Children Tic Disorder
- Journal of Traditional Chinese Medicine Vol. 50, Issue 5, Pages: 408-412(2009)
- 作者机构：
  
  1. 上海交通大学医学院附属新华医院中医科
  2. 上海交通大学医学院
  3. 上海中医药大学附属龙华医院
- 作者简介：
- 基金信息：
- DOI：10.13288/j.11-2166/r.2009.05.047
  CLC： R272
- Published：2009
- 稿件说明：
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[1]吴敏,肖光华,张建明,张欣,马博,王树霞,周亚兵,张婧延.祛风止动方治疗儿童抽动障碍31例临床研究[J].中医杂志,2009,50(05):408-412.

WU Min1, XIAO Guanghua2, ZHANG Jianming1, et al. Clinical Study on the Effect of Qufeng Zhidong Decoction on 31 Cases of Children Tic Disorder[J]. Journal of Traditional Chinese Medicine2009, 50(5): 408-412.
[1]吴敏,肖光华,张建明,张欣,马博,王树霞,周亚兵,张婧延.祛风止动方治疗儿童抽动障碍31例临床研究[J].中医杂志,2009,50(05):408-412. DOI： 10.13288/j.11-2166/r.2009.05.047.

WU Min1, XIAO Guanghua2, ZHANG Jianming1, et al. Clinical Study on the Effect of Qufeng Zhidong Decoction on 31 Cases of Children Tic Disorder[J]. Journal of Traditional Chinese Medicine2009, 50(5): 408-412. DOI： 10.13288/j.11-2166/r.2009.05.047.

摘要

目的评价祛风止动方治疗儿童抽动障碍（TD）的临床疗效与不良反应。方法将入选患儿随机分为中药组（31例）和西药组（30例）

中药组以祛风止动方治疗

西药组予氟哌啶醇和苯海索片。12周为1个疗程

观察2个疗程

以耶鲁综合抽动严重程度量表（YGTSS）、抽动症状评分量表（TSSS）、中医证候评分量表（TCMSSS）以及治疗副反应量表（TESS）、实验室检查评价临床疗效与不良反应。结果中药组和西药组总有效率分别为100%、60.0%

差异有统计学意义（P<0.05）;在各项评分方面中药组均优于西药组（P<0.05）。结论祛风止动方能显著改善TD患儿抽动症状及体征

且无毒副作用。

Abstract

Objective To assess the effect and adverse effect of Qufeng Zhidong Decoction （Decoction for Dispelling wind to stop abnormal movements） on children Tic Disorder （TD）. Methods The enrolled patients were randomized into TCM group （31 cases） and western medicine group （30 cases）. The former was treated with Qufeng Zhidong Decoction while the latter treated with haloperidol and trihexyphenidyl. Twelve weeks was of one course of treatment. Two courses were observed. The therapeutic and adverse effects were assessed by Yale Global Tic Severity Scale （YGTSS）

Tic Symptom Score Scale （TSSS）

Traditional Chinese Medicine Syndrome Score Scale （TCMSSS）

Treatment Emergent Symptom Scale （TESS） and laboratory examinations. Results The total effective rate of TCM group and western medicine groups were 100% and 60.0% respectively

the difference was significant （P>0.05）. All the scores of TCM group were better than those of western medicine group （P<0.05）. Conclusion Qufeng Zhidong Decoction could significantly improve symptoms and signs of TD children without adverse effect.

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