Objective To observe the influence of Wenban Recipe（Recipe for stabilizing the atherosclerotic plaques） on the stability of atherosclerotic plaques of rabbits.Methods The 56 white rabbits were randomized into blank group

model group

simvastatin group

and Wenban Recipe group

with 14 rabbits in each.The atherosclerosis models were made through feeding high-fat diet for 12 weeks and then medication was given.The rabbits were killed 8 weeks later

and the serum was collected for measuring total cholesterol（TC）

triglyceride（TG）

high density lipoprotein cholesterol（HDL-C）

and low density lipoprotein cholesterol（LDL-C）;the aortic pathological section was used to observe the areas of plaque and lipid core and the thickness of intima

media and fibrous cap.Results The levels of TC

TG

and LDL-C of Wenban Recipe group were significantly lower than those of the model group（P<0.01）

while the level of HDL-C in all groups was without statistical difference.Compared with the model group

the areas of plaque and lipid core and the thickness of intima

and intima/media of Wenban Recipe group were significantly decreased（P<0.01）

but thickness of fibrous cap and fibrous cap thickness/lipid core area were significantly increased（P<0.01）.Conclusion Wenban Recipe can decrease the blood fat in improving the inner structure of atherosclerotic plaques

being effective for stabilizing the plaques.