Objective To observe the effect of Wenyang Huoxue Recipe（Recipe for warming yang and activating blood） on clinical symptoms

vascular endothelial function and inflammatory reaction of acute coronary syndrome（ACS） patients.Methods The 80 ACS patients were randomized into a treatment group and a control group with 40 cases in each.The control group was treated routinely with western medicine

based on which the treatment group was administered Wenyang Huoxue Recipe.The indices including TCM syndrome

effect on angina pectoris

serum endothelin（ET）

tumor necrosis factor α（TNF-α）

Interleukin-6（IL-6）

thromboxane B2（TXB2）

and 6-keto-prostaglandin F（6-keto-PGF） of two groups before and after treatment were observed.Results Total effective rate of the treatment group and control group was 82.5% and 62.5% respectively

total effective rate of angina pectoris was 80% and 65% respectively

the difference between groups was significant（P<0.05）.After treatment

serum IL-6

TNF-α

TXB2 and ET of the treatment group were significantly decreased

while 6-keto-PGF was significantly increased（P<0.05 or P<0.01）.Conclusion Wenyang Huoxue Recipe functions to improve symptoms

regulate vascular endothelial function and reduce inflammatory reaction in the treatment of ACS patients.