Effect of Erzhi Tiangui Granule on Endometrial Receptivity of Infertility Induced by Luteal Phase Deficiency

LIANG Fang1; HE Ruiyan2; LI Tingting2

doi:10.13288/j.11-2166/r.2009.11.008

您当前的位置：

首页 >

文章列表页 >

Effect of Erzhi Tiangui Granule on Endometrial Receptivity of Infertility Induced by Luteal Phase Deficiency

更新时间：2021-11-17

- Effect of Erzhi Tiangui Granule on Endometrial Receptivity of Infertility Induced by Luteal Phase Deficiency
- Journal of Traditional Chinese Medicine Vol. 50, Issue 11, Pages: 988-990(2009)
- 作者机构：
  
  1. 山东中医药大学附属医院中西医结合生殖与遗传中心
  2. 山东中医药大学第一临床学院
- 作者简介：
- 基金信息：
- DOI：10.13288/j.11-2166/r.2009.11.008
  CLC： R271.14
- Published：2009
- 稿件说明：
移动端阅览
[1]连方,贺瑞燕,李婷婷.二至天癸颗粒对黄体功能不健性不孕症患者子宫内膜容受性的影响[J].中医杂志,2009,50(11):988-990.

LIANG Fang1, HE Ruiyan2, LI Tingting2. Effect of Erzhi Tiangui Granule on Endometrial Receptivity of Infertility Induced by Luteal Phase Deficiency[J]. Journal of Traditional Chinese Medicine2009, 50(11): 988-990.
[1]连方,贺瑞燕,李婷婷.二至天癸颗粒对黄体功能不健性不孕症患者子宫内膜容受性的影响[J].中医杂志,2009,50(11):988-990. DOI： 10.13288/j.11-2166/r.2009.11.008.

LIANG Fang1, HE Ruiyan2, LI Tingting2. Effect of Erzhi Tiangui Granule on Endometrial Receptivity of Infertility Induced by Luteal Phase Deficiency[J]. Journal of Traditional Chinese Medicine2009, 50(11): 988-990. DOI： 10.13288/j.11-2166/r.2009.11.008.

摘要

目的探讨二至天癸颗粒对黄体功能不健所致不孕症患者的治疗作用及机理。方法将60例黄体功能不健性不孕症患者随机分为二至天癸颗粒组（试验组）30例和六味地黄颗粒组（对照组）30例

观察两组治疗后中医证候改善情况

黄体中期血清雌二醇（E2）、孕酮（P）水平

黄体中期子宫内膜白血病抑制因子（LIF）表达

以及两组患者的妊娠率。结果治疗后试验组患者中医证候改善程度优于对照组（P<0.05）。试验组黄体中期血清P水平及子宫内膜LIF表达量均明显高于对照组（P<0.05）;两组血清E2虽较治疗前有所降低

但差异均无统计学意义（P>0.05）。试验组妊娠率亦高于对照组（P<0.05）。结论二至天癸颗粒治疗黄体功能不健性不孕症可能与其提高子宫内膜LIF的表达从而影响子宫内膜容受性有关。

Abstract

Objective To study the effect and mechanism of Erzhi Tiangui Granule（Granule for promoting the uterine functions） on infertility induced by luteal phase deficiency.Methods Sixty infertility patients owing to luteal phase deficiency were randomized into the tested group（treated with Erzhi Tiangui Granule） and the control group（treated with Liuwei Dihuang Granule）

30 in each.The improvement of TCM symptoms

the serum levels of estradiol（E2） and progestone（P）

the expression of leukemia inhibiting factor（LIF） of luteal metaphase before and after treatment

and the pregnancy rate were observed.Results After treatment

the tested group was significantly better than the control group in improving the TCM symptoms（P<0.05）;the serum level of progestone and LIF expression in the tested group were significantly higher than those in the control group（P<0.05）;the serum level of E2 in both groups was lower than that before treatment

but without significant difference（P>0.05）;the pregnancy rate in the tested group was higher than that in the control group（P<0.05）.Conclusion The mechanism of Erzhi Tiangui Granule treating infertility caused by luteal phase deficiency might be related to its function in increasing the LIF expression to improve the endometrial receptivity.

关键词

Keywords

references

查看原文

Views

431

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

Expertise of XU Runsan in Treating Gynecological Disorders with Insect-Based Medicinal Herbs

Effects of Bushen Tiaojing Formula （补肾调经方） on Blastocyst Cell Apoptosis and Endoplasmic Reticulum Stress in Repeated Controlled Ovarian Stimulation Model Mice

Discussion on the Application of Warm-Yang Method in Polycystic Ovary Syndrome Infertility

Effect of Modified Shoutai Pill （寿胎丸加味方） on Inflammatory Reaction and Expression of Endometrial Receptivity-Related Factors in A Rat Model of Polycystic Ovary Syndrome and Miscarriage with High Testosterone-Insulin Resistance

Clinical Experience Applying the "Kidney-supplementing and Blood-invigorating" Method to Treat Infertility of Repeated Implantation Failure

Related Author

XU Lin

GUO Ming

ZHAO Hong

许润三

XIONG Wenyan

SHI Beibei

SHEN Lulu

DU Huilan

Related Institution

Xiyuan Hospital，China Academy of Chinese Medical Sciences

Japan Friendship Hospital

Collaborative Innovation Center for Reproductive Diseases of Integrated Traditional Chinese and Western Medicine in Hebei Province

School of Integrated Traditional Chinese and Western Medicine，Hebei University of Chinese Medicine

China Academy of Chinese Medical Sciences

Address：No.16, Nanxiao street, Dongzhimen, Dongcheng District, Beijing Postal code：100700
Tel：010-64035632 Email：jtcmcn@188.com
Technical support is provided by Beijing Founder electronics co., LTD 京ICP备09064830号-19 京公网安备11010102007558号
It is recommended to read the content of this site in Chrome&IE9+. Please switch to extreme mode in browser 360.
Cookies We use cookies to help provide and enhance our service and tailor content. By continuing, you agree to the use of cookies.

⁰